Photodynamic Therapy With Red Leds in Microorganisms Related to Halitosis (halitosis)
Halitosis
About this trial
This is an interventional treatment trial for Halitosis focused on measuring Halitosis, Photodynamic Therapy, qPCR
Eligibility Criteria
Inclusion Criteria:
- Included in this study are young adults between the ages of 18 and 25, with an informed consent form and authorization for the diagnosis and treatment of halitosis.
Young adults diagnosed with halitosis presenting Oralchroma S2H ≥ 112 ppb and / or CH3SH ≥ 26.
Exclusion Criteria:
- With dentofacial anomalies,
- In orthodontic and / or orthopedic treatment,
- Using a removable device, implant and / or prosthesis,
- With periodontal disease,
- With teeth with carious lesions,
- In cancer treatment,
- On antibiotic treatment up to 1 month prior to the survey,
- Pregnant,
- With hypersensitivity to the photosensitizer to be used.
Sites / Locations
- University of Nove de JulhoRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Experimental
aPDT group
Tongue Scraper
aPDT and tongue scraper
For photodynamic therapy will be used an equipment developed for this project with emission of red LED (660nm) and tip of 2.84 cm² .One session of the Chimiolux® photosensitizing aPDT will be performed, at a concentration of 0.005%, to be applied enough to cover the middle third and back of the tongue for 2 minutes for incubation. Four points will be irradiated with a distance of 1cm between the points, considering the scattering halo and the effectiveness of aPDT. The LED apparatus will be previously calibrated with wavelength 660 nm, with energy of 72 J, power of 800 mW for 90 seconds per point, creep of 282mW / cm².
Tongue scraper 10 times in the tongue, from the back to the front.
Tongue scraper 10 times in the tongue, from the back to the front. For aPDT will be used an equipment developed for this project with emission of red LED (660nm) and tip of 2.84 cm² . One session of the Chimiolux® photosensitizing aPDT will be performed, at a concentration of 0.005%, to be applied enough to cover the middle third and back of the tongue for 2 minutes for incubation. Four points will be irradiated with a distance of 1cm between the points. Based on previous studies carried out with the aPDT for the treatment of halitosis the apparatus will be previously calibrated with wavelength 660 nm, with energy of 72 J, power of 800 mW for 90 seconds per point, creep of 282mW / cm².