An Adaptive Intervention for Depression Among Latinos Living With HIV (Latino-SMART)
Depression
About this trial
This is an interventional treatment trial for Depression focused on measuring Depression, HIV, Latinos, Sequential multiple assignment randomized trial designs, Mobile health, Cognitive-behavioral therapy
Eligibility Criteria
Inclusion Criteria:
- HIV positive
- 18 years of age and older
- Self identifies as Latino/Hispanic
- Fluent in English or Spanish
- Receives HIV care at study site clinic
- Has a moderate depression severity score or higher (Patient Health Questionnaire-9 score >9; PHQ)
- Agrees to discuss depression, treatment preferences, and mobile health
- Owns a mobile phone that can send/receive short-message service (SMS) text messages
- Agrees to participate in the intervention that lasts three months
- Agrees to have medical and clinical data abstracted one year after baseline
- Able and willing to consent to participate
Exclusion Criteria:
- Not HIV positive
- Under 18 years of age
- Does not self-identify as Latino/Hispanic
- Not fluent in English or Spanish
- Does not receive primary HIV care at the study site
- Has a less than moderate depression severity score (Patient Health Questionnaire-9 score ≤9; PHQ)
- Does not agree to discuss depression, treatment preferences, and mobile health
- Does not owns a mobile phone that can send/receive short-message service (SMS) text messages
- Does not agree to participate in the intervention that lasts three months
- Does not agree to have medical and clinical data abstracted one year after baseline
- Not able and willing to consent to participate
Sites / Locations
- Ward 86 HIV Clinic, Zuckerberg San Francisco General Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Behavioral Activation Therapy
Behavioral Activation Therapy & mHealth
During the initial stage treatment, the active comparator arm is the behavioral activation (BAT) program intervention. BAT is informed by behavioral theory and has been shown to be a highly efficacious treatment for depression. A total of five, 1-hour sessions will be delivered every two weeks. During Session 1, the focus will be on providing an introduction to BAT, as well as building "confianza" (mutual trust) between the patient and provider. Sessions 2 & 3 will review the initial session, introduce "high" value activities and barriers to BAT protocols. Sessions 4 & 5 will review progress, challenges & maintenance strategies.
During the initial stage treatment, the experimental arm will deliver a BAT program identical to the active comparator arm, as well as a mobile health (mHealth) component in the form of one-way and two-way SMS text-messages. Direct personalized text-messages will be delivered twice a week to facilitate engagement with the BAT intervention activities. One-way messages will be sent as appointment and BAT adherence reminders. Two-way messages will be sent once a week during a set block of protected hours, creating a "mobile drop-in clinic" where messages can be sent and received.