Long-duration EPBD vs EST for Removal of Biliary Stones
Cholangiopancreatography, Endoscopic Retrograde
About this trial
This is an interventional treatment trial for Cholangiopancreatography, Endoscopic Retrograde focused on measuring Cholangiopancreatography, Endoscopic Retrograde
Eligibility Criteria
Inclusion Criteria:
- Consecutive patients were invited to participate by the investigators or research staff if they were at least 18 years old,
- patients who had known or suspected choledocholithiasis
Exclusion Criteria:
- active acute pancreatitis
- septic shock,
- coagulopathy (international normalized ratio >1.2, partial thromboplastic time greater than twice that of control),
- platelet count <50,000 x 103/uL,
- anticoagulation therapy within 48 hours of the procedure,
- stone diameter > 8 mm,
- bile duct diameter >15 mm, prior sphincterotomy,
- need for precut sphincterotomy for biliary access,
- biliary stricture,
- Billroth II or Roux-en-Y anatomy,
- periampullary malignancies,
- primary sclerosing cholangitis, pregnancy,
- and inability to give informed consent
Sites / Locations
- Dankook University College of MedicineRecruiting
- Wonkwang UniversityRecruiting
- Inje University, Haeundae Paik HospitalRecruiting
- St. Mary's Hospital, The Catholic University of Korea,Recruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
long duration EPBD group
endoscopic sphincterotomy (EST) group
Balloon dilation was performed using wire-guided hydrostatic balloon catheters. An 8-mm dilatation balloon was used for EPBD. Balloons were gradually inflated to maximum pressure for 3 minute, and complete inflation was verified by fluoroscopy. Stones were removed by standard techniques, including balloon or basket catheters.
After deep cannulation was achieved, a complete sphincterotomy was performed with a 25-mm pull-type sphincterotome (Clever Cut 3; KD-V411M, Olympus, Tokyo, Japan) and the sphincter was divided up to the transverse duodenal fold. A complete sphincterotomy was defined by the free passage of a fully bowed sphincterotome and the presence of spontaneous bile drainage. A complete sphincterotomy was defined by the free passage of a fully bowed sphincterotome and the presence of spontaneous bile drainage.