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Impact of Cognitive Control Training on Anger Symptoms and Reactive Aggression

Primary Purpose

Anger

Status
Completed
Phase
Not Applicable
Locations
Canada
Study Type
Interventional
Intervention
Cognitive Control Training
Sham Cognitive Control Training Program
Sponsored by
Toronto Metropolitan University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Anger focused on measuring Reactive Aggression, Anger, Cognitive Control Training, Anger Rumination

Eligibility Criteria

18 Years - 65 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

1. Score of 22 or higher on the Trait Anger Scale.

Exclusion Criteria:

  1. Reports currently receiving psychological treatment or counseling for anger management difficulties.
  2. Reports changes in psychiatric medication within the last month.
  3. Endorsement of current psychosis or bipolar disorder symptoms.
  4. Indicates poor English language proficiency.
  5. Reports clinically significant suicidal ideation, intent, or plan.

Sites / Locations

  • Ryerson University

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Sham Comparator

Arm Label

Cognitive Control Training

Sham Cognitive Control Training Program

Arm Description

Participants in this arm will complete a computer-based training program two times in the lab. Participants will complete the first training session in the lab during their initial visit and they will return to the lab one week later to complete the second session.

Participants in this arm will complete a sham training program two times in the lab. The program will look similar in length and design to the experimental training program, but the content of the program will remain affectively neutral. As in the experimental condition, participants will complete the first training session in the lab during their initial visit and they will return to the lab one week later to complete the second session.

Outcomes

Primary Outcome Measures

State-Trait Anger Expression Inventory 2nd Edition
A self-report measure of the experience of anger.
Computer-based cognitive control assessment
A behavioural measure of hostility-primed cognitive control involving aggressive and neutral words.

Secondary Outcome Measures

Anger Rumination Scale
A self-report measure of the degree to individuals focus on experiences with anger. The scale is comprised of four subscales, angry after thoughts (e.g., "Whenever I experience anger, I keep thinking about it for a while"), angry memories (e.g., "I re-enact the anger episode in my mind after it has happened"), understanding causes (e.g., "When someone provokes me, I keep wondering why this should have happened to me"), and thoughts of revenge (e.g. "I have difficulty forgiving people who have hurt me."). Participants will be asked to read each item and rate it in terms of how well it reflects their experience on a 4-point scale from 1 ("almost never") to 4 ("almost always"). Totals for each sub scale will be summed to produce a total score (range: 19-76), with higher scores indicating a greater propensity for rumination.
Depression and Anxiety Stress Scale-21 (DASS-21)
A self-report measure of depression, anxiety, and stress symptoms.Items are summed for each subscale to create subscale totals (i.e., depression, anxiety, and stress), with higher scores reflecting more severe emotional distress. Symptom score ranges include: normal (0-4), mild (5-6), moderate (7-10), severe (11-13), and extremely severe (14+).
Dot probe task
A behavioural measure of attentional bias towards angry faces.
Adult Temperament Questionnaire (Effortful Control section)
A self-report measure of one's ability to suppress inappropriate approach behavior, to perform an action when there is a strong tendency to avoid it, and to shift or focus behaviour.
Reactive-Proactive Aggression Questionnaire
A self-report measure of an individual's propensity for reactive aggression.
Taylor Aggression Paradigm
A behavioural measure of reactive aggression.

Full Information

First Posted
September 22, 2018
Last Updated
March 23, 2020
Sponsor
Toronto Metropolitan University
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1. Study Identification

Unique Protocol Identification Number
NCT03684031
Brief Title
Impact of Cognitive Control Training on Anger Symptoms and Reactive Aggression
Official Title
Impact of Cognitive Control Training on Anger Symptoms and Reactive Aggression (Anger Study)
Study Type
Interventional

2. Study Status

Record Verification Date
March 2020
Overall Recruitment Status
Completed
Study Start Date
April 30, 2019 (Actual)
Primary Completion Date
March 13, 2020 (Actual)
Study Completion Date
March 13, 2020 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Toronto Metropolitan University

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
High trait anger is a personality construct characterized by elevations in the frequency, duration, and intensity of anger episodes. According to many social cognitive theories, hostile interpretations of everyday situations contribute to the development and maintenance of anger symptoms. This study will examine the effectiveness of a computer-based cognitive control training task.
Detailed Description
Difficulties with anger control are reported in a number of psychological conditions and are associated with social problems, such as dating violence and workplace violence. High trait anger is a personality construct characterized by elevations in the frequency, duration, and intensity of anger episodes. However, the cognitive processes contributing to high trait anger are still poorly understood. According to the Integrative Cognitive Model of Anger and Reactive Aggression (ICM), three cognitive processes jointly contribute to the experience of high trait anger and reactive aggression: 1) hostile interpretation biases; 2) cognitive control; and 3) anger rumination. The proposed study will evaluate the validity of this model in relation to cognitive control using a computer-based cognitive control training (CCT) program.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Anger
Keywords
Reactive Aggression, Anger, Cognitive Control Training, Anger Rumination

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Participant
Allocation
Randomized
Enrollment
50 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Cognitive Control Training
Arm Type
Experimental
Arm Description
Participants in this arm will complete a computer-based training program two times in the lab. Participants will complete the first training session in the lab during their initial visit and they will return to the lab one week later to complete the second session.
Arm Title
Sham Cognitive Control Training Program
Arm Type
Sham Comparator
Arm Description
Participants in this arm will complete a sham training program two times in the lab. The program will look similar in length and design to the experimental training program, but the content of the program will remain affectively neutral. As in the experimental condition, participants will complete the first training session in the lab during their initial visit and they will return to the lab one week later to complete the second session.
Intervention Type
Behavioral
Intervention Name(s)
Cognitive Control Training
Intervention Description
A computer-based flanker task that aims to reinforce the recruitment of cognitive control in the presence of hostile/aggressive stimuli.
Intervention Type
Behavioral
Intervention Name(s)
Sham Cognitive Control Training Program
Intervention Description
A placebo version of the computer-based cognitive control training. Designed to appear similar to the experimental task, but will not reinforce the recruitment of cognitive control in the presence of hostile/aggressive stimuli.
Primary Outcome Measure Information:
Title
State-Trait Anger Expression Inventory 2nd Edition
Description
A self-report measure of the experience of anger.
Time Frame
Administered two times over the course of one week. Changes will be examined from visit 1 (before CCT training program) to visit 2 (after CCT training program)
Title
Computer-based cognitive control assessment
Description
A behavioural measure of hostility-primed cognitive control involving aggressive and neutral words.
Time Frame
Administered two times over the course of one week. Changes will be examined from visit 1 (before CCT training program) to visit 2 (after CCT training program)
Secondary Outcome Measure Information:
Title
Anger Rumination Scale
Description
A self-report measure of the degree to individuals focus on experiences with anger. The scale is comprised of four subscales, angry after thoughts (e.g., "Whenever I experience anger, I keep thinking about it for a while"), angry memories (e.g., "I re-enact the anger episode in my mind after it has happened"), understanding causes (e.g., "When someone provokes me, I keep wondering why this should have happened to me"), and thoughts of revenge (e.g. "I have difficulty forgiving people who have hurt me."). Participants will be asked to read each item and rate it in terms of how well it reflects their experience on a 4-point scale from 1 ("almost never") to 4 ("almost always"). Totals for each sub scale will be summed to produce a total score (range: 19-76), with higher scores indicating a greater propensity for rumination.
Time Frame
Administered two times over the course of one week. Changes will be examined from visit 1 (before CCT training program) to visit 2 (after CCT training program)
Title
Depression and Anxiety Stress Scale-21 (DASS-21)
Description
A self-report measure of depression, anxiety, and stress symptoms.Items are summed for each subscale to create subscale totals (i.e., depression, anxiety, and stress), with higher scores reflecting more severe emotional distress. Symptom score ranges include: normal (0-4), mild (5-6), moderate (7-10), severe (11-13), and extremely severe (14+).
Time Frame
Administered two times over the course of one week. Changes will be examined from visit 1 (before CCT training program) to visit 2 (after CCT training program)
Title
Dot probe task
Description
A behavioural measure of attentional bias towards angry faces.
Time Frame
Administered two times over the course of one week. Changes will be examined from visit 1 (before CCT training program) to visit 2 (after CCT training program)
Title
Adult Temperament Questionnaire (Effortful Control section)
Description
A self-report measure of one's ability to suppress inappropriate approach behavior, to perform an action when there is a strong tendency to avoid it, and to shift or focus behaviour.
Time Frame
Administered two times over the course of one week. Changes will be examined from visit 1 (before CCT training program) to visit 2 (after CCT training program)
Title
Reactive-Proactive Aggression Questionnaire
Description
A self-report measure of an individual's propensity for reactive aggression.
Time Frame
Administered two times over the course of one week. Changes will be examined from visit 1 (before CCT training program) to visit 2 (after CCT training program)
Title
Taylor Aggression Paradigm
Description
A behavioural measure of reactive aggression.
Time Frame
Administered one time over the course of one week. Participants will be exposed to the paradigm following the second training session.]

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
65 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: 1. Score of 22 or higher on the Trait Anger Scale. Exclusion Criteria: Reports currently receiving psychological treatment or counseling for anger management difficulties. Reports changes in psychiatric medication within the last month. Endorsement of current psychosis or bipolar disorder symptoms. Indicates poor English language proficiency. Reports clinically significant suicidal ideation, intent, or plan.
Facility Information:
Facility Name
Ryerson University
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5B 2K3
Country
Canada

12. IPD Sharing Statement

Plan to Share IPD
No
IPD Sharing Plan Description
The results of this study will be disseminated through conference presentations, journal publications, and through the lab website. Anonymized aggregate participant data may be made available upon request to a publishing journal or individual research group. However, research groups interested in accessing anonymized data will be required to submit a proposal detailing their intended use of the data. Their qualifications will be reviewed based on their proposal and CVs. Individual research groups approved for access will be required to agree to not attempt to re-identify participants, not further distribute data, and not use the data for purposes other than specified in their original proposal. No individual data will be shared.
Citations:
PubMed Identifier
18453470
Citation
Wilkowski BM, Robinson MD. The cognitive basis of trait anger and reactive aggression: an integrative analysis. Pers Soc Psychol Rev. 2008 Feb;12(1):3-21. doi: 10.1177/1088868307309874. Epub 2007 Dec 18.
Results Reference
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Impact of Cognitive Control Training on Anger Symptoms and Reactive Aggression

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