Efficacy of NPWT in Reducing the Incidence of Wound Infection After Pancreatic Surgery
Surgical Site Infection
About this trial
This is an interventional prevention trial for Surgical Site Infection focused on measuring negative pressure wound therapy, wound infection, pancreaticoduodenectomy, total pancreatectomy, surgical palliation of pancreatic cancer
Eligibility Criteria
Inclusion Criteria:
- Age > 18
- Informed consent
- HPB clean-contaminated procedures (PD, TP and GEA/HJ)
- Median laparotomy
- Compliance with a follow-up protocol
High risk for SSI (at least one of the following):
- Body Mass Index > 30kg/m2
- Diabetes mellitus type I or II
- Use of steroids
- Neoadjuvant therapy
- ASA ≥ 3
- Charlson Comorbidity Index 1
- Time of surgery > 360'
- Estimated blood loss > 1L
Exclusion Criteria:
- Previous open surgery of the abdomen
- Unable to give informed consent
Sites / Locations
- Ospedale Policlinico GB Rossi
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Negative wound pressure device (PICO)
Standard sterile dressing
The disposable negative wound pressure device (PICO) will be used to cover the midline incision. The dressing is changed on POD3 and removed on POD7. Data are collected on POD3, POD7 and POD30.
The OPsite post-op visible standard sterile dressing will be used to cover the midline incision. Dressing is changed q48h. Data are collected on POD3, POD7 and POD30.