Bariatric Surgery and Consequences for Mother and Baby in Pregnancy (BAMBI)
Hypoglycemia Non-Diabetic, Gastric Bypass Status Complicating Pregnancy, Birth, or Puerperium
About this trial
This is an interventional diagnostic trial for Hypoglycemia Non-Diabetic focused on measuring Pregnancy, Gastric bypass, Hypoglycemia, Gestational weight gain, Fetal growth
Eligibility Criteria
Inclusion Criteria:
- GB group: pregnant women with RYGB (n = 20)
- non-GB group: pregnant women matched on age, prepregnancy-BMI and parity (n = 20)
- neonates: offspring of abovementioned women (n = 40)
Exclusion Criteria:
- multiple pregnancy
- age below 18 and above 45 years
- ongoing smoking and substance abuse
- severe psychiatric disorder
- severe chronic disease
diabetes
- women with overt diabetes at inclusion (HbA1c ≥ 48 mmol/l and/or fasting p-glucose ≥ 7 mmol/l)
- women with pre-gestational diabetes (type1 or 2) prior to RYGB
- women with Gestational Diabetes Mellitus (GDM) in a previous pregnancy will not be excluded
Sites / Locations
- Odense University Hospital
- Hospital of South West Jutland
Arms of the Study
Arm 1
Arm 2
Other
Other
Women with RYGB and fetus/ child
Matched controls and fetus/ child
20 pregnant women with previous gastric bypass surgery. During pregnancy the women will be tested with mixed meal test and continuous glucose monitoring for the diagnosis of hypoglycemia. Ultrasounds of fetal growth will be performed and after birth anthropometrics of the newborn will be meaured including a DXA-scan to estimate bodycomposition.
20 pregnant women matched on age, prepregnancy-BMI and parity (n = 20). During pregnancy the women will be tested with mixed meal test and continuous glucose monitoring for the diagnosis of hypoglycemia. Ultrasounds of fetal growth will be performed and after birth anthropometrics of the newborn will be meaured including a DXA-scan to estimate bodycomposition.