Effect of Fasting on ICSI Outcomes in Poor Responders
Infertility
About this trial
This is an interventional other trial for Infertility focused on measuring Infertility, Poor ovarian reserve, Intracytoplasmic sperm injection, fasting
Eligibility Criteria
The study will include:
infertile patients with poor ovarian reserve (POR )diagnosed by low Antral follicle count (AFC)( less than 5 follicles), Elevated basal follicle-stimulating hormone (FSH) (more than 10 IU/mL) and low anti-Mullerian hormone (AMH)(less than 1.5 ng/ml), previous POR (≤three oocytes with a conventional stimulation protocol).
Women with diabetes, thyroid disorder or other endocrine dysfunctions, uterine abnormalities were excluded.Also severe oligo-astheno-teratozoospermia or azospermia are excluded.
Sites / Locations
- KasrELAiniH
Arms of the Study
Arm 1
Arm 2
Active Comparator
Other
Fasting group
Non fasting group
Patients will have periodic fasting for 4 weeks prior to the treatment cycle. The fasting method involves daily fasts of 14-16hours and restrict eating to an 8-10 hour "eating window" as 2-3 or more meals of balanced diet. They should take adequate water and non calorie beverages intake daily (2-3 liters)
no fasting, patients will have usual balanced diet as 3 meals and 2 snacks all over the day. They should take adequate water and non calorie beverages intake daily (2-3 liters)