Mechanical Insufflation-Exsufflation Compared With CPAP in Patients Admitted to an Intermediate Care Unit With Pneumonia (CoughAssist)
Pneumonia
About this trial
This is an interventional supportive care trial for Pneumonia focused on measuring mechanical insufflation-exsufflation
Eligibility Criteria
Inclusion Criteria:
- Community acquired or nosocomial pneumonia, diagnosed by new infiltrate on an x-ray chest and symptoms and/or objective findings acute lower airway infection
- 18 years or older
- able to participate in CPAP treatment 10 cm H2O for 5 minutes
- able to provide written consent
Exclusion Criteria:
- pneumothorax less than 4 weeks prior to admission
- current pleural tube
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Mechanical insufflation-exsufflation arm
CPAP arm
MIE will be given as prescribed by physician responsible at the intermediate care unit, typically every 4 hours. MIE will be administered with standard settings of insufflation 20 cm H2O and exsufflation 20 cm H2O, with possible individual changes from 10/-10 H2O up to 40/-40 H2O, and oxygen flow up to 15 l/min. The standard settings will be set to five cycles of 2 seconds insufflation, 3 seconds exsufflation with a three second pause between each cycle. Every treatment session consists of five rounds of five cycles, in all 25 insufflation/exsufflation, with time between each cycle of 30 seconds, meant used for suction.
CPAP will be given as prescribed by the physician responsible at the intermediate care unit, typically every 4 hours. CPAP will be administered with standard settings of H2O and an oxygen flow of 15L/min.