Platelet-Rich Fibrin and Anorganic Bovine Bone vs Collagen Membrane and Anorganic Bovine Bone in Intrabony Defects
Periodontal Attachment Loss, Periodontal Bone Loss, Periodontal Diseases
About this trial
This is an interventional treatment trial for Periodontal Attachment Loss focused on measuring Platelet rich fibrin, bone graft, non inferiority trial
Eligibility Criteria
Inclusion Criteria:
- a full-mouth plaque score (FMPS) 25 and a full-mouth bleeding score (FMBS) 26 < 20% at the time of surgery
- to have at least 20 teeth,;
- at least 1 tooth exhibiting vertical bone loss detected by radiographic examination (alveolar crest level [ ACL]
- bottom of the defect [ BD] distance = Bone defect depth [ BDD]) ≥ 4 mm and a probing pocket depth (PPD) ≥ 5mm when evaluated 12 weeks after phase I non- surgical therapy [ scaling and root planing ( SRP)].
Exclusion Criteria:
- no systemic diseases
- no medications affecting periodontal status during the previous 6 months
- not pregnant or lactating;
- non-smoker
- no periodontal therapy in the 2 previous years,
- no inadequate endodontic treatment, no dental mobility
Sites / Locations
- G. d'Annunzio University
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
PRF+ABB treated patients
Collagen Membrane + ABB treated patients
Periodontal surgery with Platelet Rich Fibrin is performed, after local anaesthesia, mucoperiosteal SPPFs will be raised. Anorganic bovine bone material will be applied to the entire root surfaces ; then, A prf membrane is positioned above the filling material. Finally the flap will be positionated and sutures completed by interrupted sutures.
Periodontal surgery with collagen membrane is performed, after local anaesthesia, mucoperiosteal SPPFs will be raised. Anorganic bovine bone material will be applied to the entire root surfaces ; then, A collagen membrane is positioned above the filling material. Finally the flap will be positionated and sutures completed by interrupted sutures.