Imaginal Exposure for Hoarding Disorder
Primary Purpose
Hoarding Disorder
Status
Active
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Imaginal Exposure Writing
Neutral Writing
Sponsored by
About this trial
This is an interventional basic science trial for Hoarding Disorder focused on measuring hoarding disorder, intolerance of uncertainty, experiential avoidance, imaginal exposure, clutter, attachment
Eligibility Criteria
Inclusion Criteria:
- Age 18 and older
- Any gender and all ethno-racial categories
- Hoarding Disorder primary condition
- Willing and able to understand and complete consent and study procedures
- English speaking
Exclusion Criteria:
- Severe depression
- Clinically at risk of suicide with Columbia Suicide Severity Rating Scale (C-SSRS) Suicidal Ideation Subscale of 4 or higher (i.e. suicidal intent without specific plan)
- Currently receiving Cognitive Behavioral Therapy (CBT)
Sites / Locations
- Stanford University
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Sham Comparator
Arm Label
Imaginal Exposure Writing
Neutral Writing
Arm Description
People with hoarding disorder will write for 20 minutes on each of 3 consecutive days about their worst-case scenario regarding discarding a possession (i.e., imaginal exposure).
People with hoarding disorder will write for 20 minutes on each of 3 consecutive days about what they would do if they had a day off work or school.
Outcomes
Primary Outcome Measures
Savings Inventory Revised (Frost, Steketee & Grisham, 2004; Tolin, Meunier, Frost & Steketee, 2011)
Gold-standard 23-item self-report measure of hoarding disorder symptoms. Scale scores range from 0 to 92, with higher scores indicating more severe hoarding symptoms. More severe hoarding symptoms are considered a worse outcome.
Secondary Outcome Measures
Compulsive Acquisitions Scale (Frost et al. 2002)
Self-report 18-item measure of behaviors associated with hoarding disorder (i.e., acquiring).Scale scores range from 18 to 126, with higher scores indicating more severe hoarding behaviors. More severe hoarding behaviors are considered a worse outcome.
Intolerance of Uncertainty Scale (Buhr & Dugas, 2002)
Self-report 27-item measure of a cognitive process related to hoarding called intolerance of uncertainty. Scale scores range from 27 to 135 (some items are reverse scored), with higher scores indicating more severe intolerance of uncertainty. More severe intolerance of uncertainty is considered a worse outcome.
Acceptance and Action Questionnaire - II (Hayes, Luoma, Bond, Masuda and Lillis, 2006)
Self-report 7-item measure of a cognitive process related to hoarding called experiential avoidance. Scale scores range from 7 to 49, with higher scores indicating more severe experiential avoidance. More severe hoarding behaviors are considered a worse outcome.
Continuous Performance Task
A CPT administered by computer will be given to assess attention difficulties, a hallmark feature of hoarding disorder. The scoring of the task will include 1) reaction time, with slower reaction times indicating worse attention, and 2) omission errors, which is when a stimulus is presenting and the participant does not respond. Higher omission errors indicate worse attention.
Full Information
NCT ID
NCT03734705
First Posted
November 5, 2018
Last Updated
April 10, 2023
Sponsor
Stanford University
Collaborators
Brain & Behavior Research Foundation
1. Study Identification
Unique Protocol Identification Number
NCT03734705
Brief Title
Imaginal Exposure for Hoarding Disorder
Official Title
Efficacy and Feasibility of Intensive Imaginal Exposure for Hoarding Disorder
Study Type
Interventional
2. Study Status
Record Verification Date
April 2023
Overall Recruitment Status
Active, not recruiting
Study Start Date
January 13, 2020 (Actual)
Primary Completion Date
December 31, 2023 (Anticipated)
Study Completion Date
December 31, 2024 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Stanford University
Collaborators
Brain & Behavior Research Foundation
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
The present study will test a potential new treatment strategy, imaginal exposure, for hoarding disorder. Although cognitive behavioral therapy often reduces hoarding, some people do not want to start, or cannot handle, that option. To help such individuals, the present study will provide imaginal exposure therapy to people with hoarding disorder, wherein they imagine discarding possessions as a way of becoming acclimated to the idea. We predict that imaginal exposure will improve hoarding symptoms as well as two psychological experiences linked to the condition: intolerance of uncertainty and emotional avoidance.
Detailed Description
Hoarding disorder is a common mental illness characterized by difficulty parting with possessions and by clutter that makes living spaces unusable. Cognitive behavioral therapy (CBT) is an effective treatment for hoarding disorder, but new approaches are needed to engage those who are reluctant to start or cannot tolerate CBT. Both intolerance of uncertainty and emotional avoidance are linked to hoarding disorder and may interfere with treatment engagement. Imaginal exposure, a therapeutic technique which involves repeatedly imagining feared scenarios and experiencing the evoked emotions, effectively targets both intolerance of uncertainty and emotional avoidance. The present study is the first to test whether imagining discarding possessions can improve hoarding symptoms more than does a control exercise. We hypothesize that compared to a control exercise, imaginal exposure will improve hoarding symptoms, intolerance of uncertainty and emotional avoidance.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Hoarding Disorder
Keywords
hoarding disorder, intolerance of uncertainty, experiential avoidance, imaginal exposure, clutter, attachment
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Participant
Masking Description
Participants will be randomly assigned to imaginal exposure writing intervention or neutral control writing.
Allocation
Randomized
Enrollment
30 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
Imaginal Exposure Writing
Arm Type
Experimental
Arm Description
People with hoarding disorder will write for 20 minutes on each of 3 consecutive days about their worst-case scenario regarding discarding a possession (i.e., imaginal exposure).
Arm Title
Neutral Writing
Arm Type
Sham Comparator
Arm Description
People with hoarding disorder will write for 20 minutes on each of 3 consecutive days about what they would do if they had a day off work or school.
Intervention Type
Behavioral
Intervention Name(s)
Imaginal Exposure Writing
Intervention Description
Imaginal exposure is a psychotherapy strategy that has been studied and shown to be helpful in the improvement of symptoms (e.g., anxiety, worry) for other psychiatric conditions, including excessive worry and obsessive-compulsive disorder symptoms.
Intervention Type
Other
Intervention Name(s)
Neutral Writing
Intervention Description
Used in prior research as a control condition for imaginal exposure. Neutral writing will involve writing about what one would do on a day off work or school.
Primary Outcome Measure Information:
Title
Savings Inventory Revised (Frost, Steketee & Grisham, 2004; Tolin, Meunier, Frost & Steketee, 2011)
Description
Gold-standard 23-item self-report measure of hoarding disorder symptoms. Scale scores range from 0 to 92, with higher scores indicating more severe hoarding symptoms. More severe hoarding symptoms are considered a worse outcome.
Time Frame
1-week
Secondary Outcome Measure Information:
Title
Compulsive Acquisitions Scale (Frost et al. 2002)
Description
Self-report 18-item measure of behaviors associated with hoarding disorder (i.e., acquiring).Scale scores range from 18 to 126, with higher scores indicating more severe hoarding behaviors. More severe hoarding behaviors are considered a worse outcome.
Time Frame
1-week
Title
Intolerance of Uncertainty Scale (Buhr & Dugas, 2002)
Description
Self-report 27-item measure of a cognitive process related to hoarding called intolerance of uncertainty. Scale scores range from 27 to 135 (some items are reverse scored), with higher scores indicating more severe intolerance of uncertainty. More severe intolerance of uncertainty is considered a worse outcome.
Time Frame
1-week
Title
Acceptance and Action Questionnaire - II (Hayes, Luoma, Bond, Masuda and Lillis, 2006)
Description
Self-report 7-item measure of a cognitive process related to hoarding called experiential avoidance. Scale scores range from 7 to 49, with higher scores indicating more severe experiential avoidance. More severe hoarding behaviors are considered a worse outcome.
Time Frame
1-week
Title
Continuous Performance Task
Description
A CPT administered by computer will be given to assess attention difficulties, a hallmark feature of hoarding disorder. The scoring of the task will include 1) reaction time, with slower reaction times indicating worse attention, and 2) omission errors, which is when a stimulus is presenting and the participant does not respond. Higher omission errors indicate worse attention.
Time Frame
1-week
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Age 18 and older
Any gender and all ethno-racial categories
Hoarding Disorder primary condition
Willing and able to understand and complete consent and study procedures
English speaking
Exclusion Criteria:
Severe depression
Clinically at risk of suicide with Columbia Suicide Severity Rating Scale (C-SSRS) Suicidal Ideation Subscale of 4 or higher (i.e. suicidal intent without specific plan)
Currently receiving Cognitive Behavioral Therapy (CBT)
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Katie Fracalanza, PhD
Organizational Affiliation
Stanford University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Stanford University
City
Palo Alto
State/Province
California
ZIP/Postal Code
94304
Country
United States
12. IPD Sharing Statement
Plan to Share IPD
Undecided
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Imaginal Exposure for Hoarding Disorder
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