Physiological Adaptations to Simulated Intermittent Altitude on Human Health and Performance
Altitude Hypoxia
About this trial
This is an interventional prevention trial for Altitude Hypoxia
Eligibility Criteria
Inclusion criteria:
- 18-70 years of age,
- history of good health,
- generally active to competitive athletes.
Exclusion criteria:
- History of cardiac or pulmonary disease,
- not currently active,
- unable to exercise or meet study requirements (e.g., number of sessions),
- live at altitude (>2,100m or 7,000ft).
Sites / Locations
- Mayo Clinic in Arizona
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Active Comparator
Placebo Comparator
Effect of heart rate training in simulated altitude
Effect of saturation of oxygen training in simulated altitude
Effect of optimized training in simulated altitude
Effect of placebo training in non-simulated altitude
Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining >65% max heart rate during room air based maximal peak work.
Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining 40-60% of max work rate during room air work rate and based upon saturation of oxygen of between 70-80%.
Participants will perform the more beneficial intervention (heart rate or saturation of oxygen training) to evaluate whether it improves elite athlete's training status at altitude.
Participants will perform placebo beneficial intervention (heart rate or saturation of oxygen training) to evaluate whether the optimized protocol truely improves elite athlete's training status at altitude.