Central Obesity in Cases of OAB
Urologic Diseases, Overactive Bladder Syndrome, Obesity, Abdominal
About this trial
This is an interventional diagnostic trial for Urologic Diseases focused on measuring abdominal obesity, OAB
Eligibility Criteria
Inclusion Criteria:
- patients with OAB between 18 and 40 years old.
- normal variant healthy donor as a control.
Exclusion Criteria:
Patients who have any of the following:
- Age less than 18 or more than 40 years old
- Neurogenic detrusor overactivity
- evidence of obstructed flow in absence of prolapse
- mixed urinary incontinence
- associated urethral pathology, e.g. Urethral diverticulum
- Associated bladder pathology e.g. fistula, active urinary tract infection as evidenced by positive urine culture
- previous exposure for anticholinergics or BTX-A injection.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
patients with OAB
normal variants healthy without symptoms
Patients were asked to fill (OABSS) for more accurate evaluation of bothersome degree. Waist Circumference is evaluated. The surface area of subcutaneous fat (S) and visceral (V) is calculated using slices between L4-L5 and umbilicus according to CT detection fat methods Also bladder wall thickness was calculated by measuring average bladder wall thickness at three different levels. Subcutaneous fat to visceral fat ratio was calculated. Assays for serum total and high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels were performed in the hospital's chemistry laboratory with an autoanalyzer. VAI was calculated for females as this formula like the previous study. VAI: WC/ [36.58 + (1.89 × BMI)] × TG/0.81 × 1.52/HDL. And in males: VAI: WC / [39.68 + (1.88 x BMI)] x TG/ 1.03 x 1.31/ HDL
WC is evaluated crest. The surface area of subcutaneous fat (S) and visceral (V) is calculated using slices between L4-L5 and umbilicus according to ct detection fat methods Also bladder wall thickness was calculated by measuring average bladder wall thickness at three different levels. Subcutaneous fat to visceral fat ratio was calculated. Assays for serum total and high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels were performed in the hospital's chemistry laboratory with an autoanalyzer. VAI was calculated for females as this formula like the previous study. VAI: WC/ [36.58 + (1.89 × BMI)] × TG/0.81 × 1.52/HDL. And in males:VAI: WC / [39.68 + (1.88 x BMI)] x TG/ 1.03 x 1.31/ HDL