Added Benefit of L-PRF to Autogenous Bone Graft in the Treatment of Mandibular Degree II Furcation Defects
Periodontal Attachment Loss, Periodontal Bone Loss
About this trial
This is an interventional treatment trial for Periodontal Attachment Loss focused on measuring Platlet rich fibrin, Bone graft, Furcation defects
Eligibility Criteria
Inclusion Criteria:
- a Full-Mouth Plaque Score (FMPS) and a Full-Mouth Bleeding Score (FMBS) < 20% at the time of surgery;
- to have at least 20 teeth;
- at least 1 mandibular molar with buccal or lingual degree II furcation defects, with no mobility and with horizontal CAL (HCAL) > 3 mm and vertical probing depth in the central-vestibular or central-lingual site >= 5 mm after non surgical treatment.
Exclusion Criteria:
- systemic diseases;
- medications affecting periodontal status during the previous 6 months;
- pregnant or lactating;
- smokers;
- periodontal therapy in the 2 previous years;
- periapical endodontic lesions;
- dental mobility.
Sites / Locations
- G. d'Annunzio University
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Active Comparator
OFD+ABG+L-PRF treated patients
OFD+ABG treated patients
OFD treated patients
Periodontal surgery with Leukocyte and Platelet Rich Fibrin (L-PRF) is performed, after local anaesthesia, mucoperiosteal SPPFs will be raised. Autogenous bone graft mixed with cutted L-PRF will be applied to the furcation defects; then, a L-PRF membrane is positioned above the filling material. Finally the flap will be coronally positionated and sutured by interrupted sutures.
Periodontal surgery with Autogenous Bone Graft (ABG) is performed, after local anaesthesia, mucoperiosteal SPPFs will be raised. ABG will be applied to the furcation defects. Finally the flap will be coronally positioned and sutured by interrupted sutures.
Periodontal surgery with Open Flap Debridement is performed, after local anaesthesia, mucoperiosteal SPPFs will be raised. No grafts will be applied to the furcation defects. Finally the flap will be coronally positioned and sutured by interrupted sutures.