Laryngeal Adaptation for Speech and Swallowing
Stroke, Spinocerebellar Ataxia, Cerebral Stroke
About this trial
This is an interventional treatment trial for Stroke focused on measuring speech, swallowing, rehabilitation, stroke, deglutition, dysphagia, dysarthria, laryngeal, ataxia
Eligibility Criteria
Patient Inclusion Criteria:
All stroke and ataxia
Ataxia
- DNA diagnosis of SCA6 and phenotype consistent with the DNA diagnosis
- No recessive, X-linked or mitochondrial
Stroke
- Bilateral or unilateral middle cerebral artery (MCA) stroke
- No structural abnormalities (i.e. nodules)
- Dysphagia involving laryngeal dysfunction
Stroke and ataxia with speech and swallowing disorders
- no structural abnormalities
- dysphagia involving laryngeal dysfunction
Patient Exclusion Criteria:
- Montreal Cognitive Assess. <24
- Moderate to severe hearing loss
- Barium allergy
- Other confounding speech disorder (i.e. stuttering)
- Chemo-radiation, surgical head and neck treatment
- Smoking Hx in the past 5 yrs or >5 years at any one time
- Twenty one years of age or older
- Breathing disorders or diseases
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Experimental
Experimental
Experimental
Experimental
Active Comparator
Stroke without Dysarthria
Stroke with Dysarthria
SCA6 without Dysarthria
SCA6 with Dysarthria
Age-Matched Controls
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.
Examine laryngeal adaptation across all study groups: (1) baseline measures of speech or swallowing , (2) a clinical examination of disease/condition severity and (3) the experimental paradigm.