Glioma and Exercising
High Grade Glioma
About this trial
This is an interventional supportive care trial for High Grade Glioma focused on measuring interventions of physical activity and exercising (PAE), resistance training, endurance training
Eligibility Criteria
Inclusion Criteria:
- Patients with high grade glioma (WHO III° and IV°), and undergoing radiotherapy, chemotherapy, or both
- Willing and able to follow the study intervention
- Signed written informed consent
Exclusion Criteria:
- Severe psychiatric (psychosis, suicidal behavior, substance use disorder) and somatic comorbidities (severe cardiovascular disease, severe diabetes, impairments of the musculo-skeletal system)
- patients not willing or able anymore to follow the study protocol.
Sites / Locations
- University Hospital Basel, Department of Neurosurgery
- Department of Sport, Exercise and Health, University of Basel
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
Endurance training
Resistance training
Control condition
Endurance Training (warm-up; endurance on bike; brisk walking; cooling down; group sessions; supervised; moderate and individualized exercising load): 6 weeks, 2 sessions/week, 40-60min/session
Resistance Training (warm-up; resistance training units; cooling down; group sessions; supervised; moderate and individualized exercising load): 6 weeks, 2 sessions/week, 40-60min/session
Control condition (individualized counselling, but not intended as a bona fide intervention, that is to say: not intended to actively improve participants' well-being): 6 weeks, social support and counseling,1-2 sessions/week; 30 min/session