RECONsolidation of Traumatic Memories to ResOLve Post Traumatic Stress Disorder (RECONTROLPTSD) (RECONTROLPTSD)
Posttraumatic Stress Disorder, Traumatic Brain Injury
About this trial
This is an interventional treatment trial for Posttraumatic Stress Disorder focused on measuring posttraumatic stress disorder, traumatic brain injury, cognitive behavioral therapy, exposure therapy, reconsolidation
Eligibility Criteria
Inclusion Criteria:
- Meets criteria for PTSD on the CAPS5, with past month nightmares or flashbacks.
- Willing to be randomly assigned to one of the two interventions and to complete all study measures.
- Able to exhibit capacity to understand the informed consent process, by completion of a corresponding series of questions
Exclusion Criteria:
1. history of psychosis, bipolar disorder, or active suicidal or homicidal ideation
Sites / Locations
- Uniformed Services University of Health Sciences (USUHS)Recruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Reconsolidation of Traumatic Memories (RTM)
Prolonged Exposure (PE)
Participants in each arm of the study will receive up to 10 90-minute manualized treatment sessions. RTM will follow a manual developed by the Research and Recognition Project, who will also train and supervise the therapists. It is anticipated that these treatments will most often be administered once per week for 10 weeks. To best meet participant needs, we will allow therapy in either arm to be "massed" in the pattern recently reported by Foa et al. for PE, with sessions separated by at least 24 hours over two weeks. This schedule has been used with both RTM and PE without hurting response rates, and may reduce drop-out rates. Participants who achieve remission of their PTSD before 10 sessions, measured by a PCL5 <34, can decide with their therapist whether early cessation of therapy is appropriate.
Participants in each arm of the study will receive up to 10 90-minute manualized treatment sessions. PE will follow a manual written by the Foa and colleagues, and the therapists will be trained by expert trainers from the Center for Deployment Psychology. It is anticipated that these treatments will most often be administered once per week for 10 weeks. To best meet participant needs, we will allow therapy in either arm to be "massed" in the pattern recently reported by Foa et al. for PE, with sessions separated by at least 24 hours over two weeks. This schedule has been used with both RTM and PE without hurting response rates, and may reduce drop-out rates. Participants who achieve remission of their PTSD before 10 sessions, measured by a PCL5 <34, can decide with their therapist whether early cessation of therapy is appropriate.