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Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task

Primary Purpose

Sodium Bicarbonate, Alkalosis, Metabolic, Electromyography

Status
Unknown status
Phase
Not Applicable
Locations
Brazil
Study Type
Interventional
Intervention
Sodium bicarbonate
Calcium carbonate
Sponsored by
University of Nove de Julho
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional other trial for Sodium Bicarbonate

Eligibility Criteria

20 Years - 42 Years (Adult)MaleAccepts Healthy Volunteers

Inclusion Criteria:

  • resistance trained men (minimum 12 moths resistance training experience)

Exclusion Criteria:

  • diabetes mellitus;
  • respiratory (asthma, COPD), renal, metabolic, rheumatic and cardiovascular disorders;
  • acid-base balance disorder;
  • continuous use of some type of medication;
  • use of high-protein supplementation and creatine supplementation;
  • users of anabolic steroids.

Sites / Locations

  • Nove de Julho University

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Placebo Comparator

Arm Label

Alkalosis group

Placebo group

Arm Description

The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of sodium bicarbonate

The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of Calcium Carbonate

Outcomes

Primary Outcome Measures

Electromyographic activity of the femoral quadriceps evaluated with electromyography equipment
The electromyographic activity will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets in an isokinetic dynamometer.
Peak torque assessed with isokinetic dynamometer equipment
The peak torque will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets.

Secondary Outcome Measures

Lactate assessed with portable lactometer
The lactate quantification will be performed before and after the test session characterized by the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with an interval of 1 minute between sets in an isokinetic dynamometer.

Full Information

First Posted
February 6, 2019
Last Updated
October 16, 2019
Sponsor
University of Nove de Julho
Collaborators
Marcelo Martins Kalytczak
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1. Study Identification

Unique Protocol Identification Number
NCT03837886
Brief Title
Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task
Official Title
Sodium Bicarbonate Supplementation Promotes Changes in Performance, Muscle Activity and Strength of Individuals Trained During the Performance of Intermittent and Intense Task? Randomized, Double-blind, Crossover Trial
Study Type
Interventional

2. Study Status

Record Verification Date
October 2019
Overall Recruitment Status
Unknown status
Study Start Date
October 20, 2019 (Anticipated)
Primary Completion Date
October 30, 2019 (Anticipated)
Study Completion Date
November 30, 2019 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Nove de Julho
Collaborators
Marcelo Martins Kalytczak

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The aim of this study was to verify if sodium bicarbonate (NaHCO3) suplementation promotes changes in the performance, muscular activity and strength of individuals trained during the intermittent and intense task . Twelve trained adult men will participate in this randomized, double-blind, crossover clinical trial. Each participant should receive two types of intervention with a 14-day interval between conditions: alkalosis (ALK) in which gelatinous capsules containing 0.3 g.kg -1 of NaHCO 3 and placebo (PLA) are administered, in which 0.3 g.kg-1 of Calcium Carbonate (CaCO3). The following results will be considered: electromyographic activity (EMG) of the quadriceps muscle, peak torque, pH, lactate, and perception of effort, recovery and pain questionnaires, which will be collected during intermittent and high intensity DI protocol. ANOVA of repeated measures will be used to verify possible differences between groups.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Sodium Bicarbonate, Alkalosis, Metabolic, Electromyography, Fatigue

7. Study Design

Primary Purpose
Other
Study Phase
Not Applicable
Interventional Study Model
Crossover Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
12 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Alkalosis group
Arm Type
Experimental
Arm Description
The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of sodium bicarbonate
Arm Title
Placebo group
Arm Type
Placebo Comparator
Arm Description
The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of Calcium Carbonate
Intervention Type
Dietary Supplement
Intervention Name(s)
Sodium bicarbonate
Intervention Description
The subjects should ingest 0.3g.kg of sodium bicarbonate 90 minutes before the beginning of the protocol task.
Intervention Type
Dietary Supplement
Intervention Name(s)
Calcium carbonate
Intervention Description
The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of Calcium Carbonate
Primary Outcome Measure Information:
Title
Electromyographic activity of the femoral quadriceps evaluated with electromyography equipment
Description
The electromyographic activity will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets in an isokinetic dynamometer.
Time Frame
60 minutes
Title
Peak torque assessed with isokinetic dynamometer equipment
Description
The peak torque will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets.
Time Frame
60 minutes
Secondary Outcome Measure Information:
Title
Lactate assessed with portable lactometer
Description
The lactate quantification will be performed before and after the test session characterized by the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with an interval of 1 minute between sets in an isokinetic dynamometer.
Time Frame
15 seconds

10. Eligibility

Sex
Male
Minimum Age & Unit of Time
20 Years
Maximum Age & Unit of Time
42 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: resistance trained men (minimum 12 moths resistance training experience) Exclusion Criteria: diabetes mellitus; respiratory (asthma, COPD), renal, metabolic, rheumatic and cardiovascular disorders; acid-base balance disorder; continuous use of some type of medication; use of high-protein supplementation and creatine supplementation; users of anabolic steroids.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Marcelo M Kalytczak, PhD
Phone
55 11 981595139
Email
marcelomkal@hotmail.com
Facility Information:
Facility Name
Nove de Julho University
City
São Paulo
ZIP/Postal Code
06454050
Country
Brazil

12. IPD Sharing Statement

Plan to Share IPD
Undecided

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Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task

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