Interventions to Help Infants Recover in the Hospital
Infant Apnea, Neonatal Abstinence Syndrome, Sleep
About this trial
This is an interventional supportive care trial for Infant Apnea focused on measuring Prematurity, Neonatal Abstinence Syndrome, Autonomic Function, Sleep, Stochastic Resonance, Newborn/Infant
Eligibility Criteria
Inclusion Criteria:
- Pre-term infants (>30 wks PMA) and full-term newborns receiving care since birth in the NICU/CCN.
- Infants/Children receiving care in the PICU/PIU (may have had a history of prematurity).
- May be with or without in utero opioid exposure and/or other drug exposure (prescribed or illicit).
- May have received or be receiving opioids and/or other treatment medications as part of their medical-care plan.
- Infants and children on respiratory support and/or with medical complications will not be excluded if these complications are potentially reversible.
Exclusion Criteria:
- Congenital anomalies of the head and/or neck.
- Significant cranial trauma.
- Hydrocephalus.
- Current or history of intraventricular hemorrhage>grade 2.
- Clinically significant cardiac shunt.
- Hemodynamic instability requiring pharmacological intervention at time of study participation.
- Documented HIV and/or MRSA positivity requiring treatment at time of study participation.
- Seizure disorder not due to opioid withdrawal.
- Invasive ventilation at time of study participation.
- Recommendation of attending physician or primary medical caregiver not to enroll the patient for any reason.
Sites / Locations
- UMass Medical School
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Experimental
Premature Infants (NICU)
Opioid-Exposed Newborns (NICU)
Hospitalized Infants (PICU)
Premature infants receiving care in the Neonatal Intensive Care Unit (NICU) will participate in up to 2 sessions with NEATCAP intervention and up to 2 sessions with SVS mattress intervention.
Opioid-exposed newborns receiving care in the Neonatal Intensive Care Unit (NICU) will participate in up to 2 sessions with NEATCAP intervention and up to 2 sessions with SVS mattress intervention.
Infants receiving treatment in the Pediatric Intensive Care or Inpatient Unit will participate in up to 2 sessions with NEATCAP intervention and up to 2 sessions with SVS mattress intervention.