Comparing the Efficacy of Two Valved Holding Chambers in Acute Wheezing (CHAMBER)
Bronchitis Obstructive, Bronchiolitis; Obstruction, Bronchospasm; Bronchitis
About this trial
This is an interventional treatment trial for Bronchitis Obstructive focused on measuring salbutamol, valved holding chamber, pMDI, inhalation therapy, children, toddlers, emergency room
Eligibility Criteria
Inclusion Criteria:
- Children (age 0.5-4 years) seeking medical aid due to respiratory distress caused by bronchial obstruction
Exclusion Criteria:
- requiring immediate admission to inpatient treatment in hospital
- peripheral capillary oxygen saturation below 85% on admission
- physician-confirmed pneumonia
- inspiratory crackles on lung auscultation
- croup
- airway foreign body
- impaired renal or liver function
- immune compromised patient
- general condition affecting the study per investigation judgement
- bronchopulmonary dysplasia
- long-acting beta-adrenoceptor agonist treatment
- recruited to the ongoing study earlier
- have been enrolled in a clinical trial within 30 days prior to admission
- not willing to participate
Sites / Locations
- Kuopio University HospitalRecruiting
- Oulu University HospitalRecruiting
- Terveystalo TampereRecruiting
- Tampere University HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Children treated with VHC 1
Children treated with VHC 2
In this group children are receiving salbutamol with valved holding chamber number 1. Otherwise the children in both groups are treated exactly the same way. The only difference is the device used to deliver the bronchodilator. Children in both arms have the same condition and the same inclusion and exclusion criteria. We only compare the efficacy of the two VHC devices.
In this group children are receiving salbutamol with valved holding chamber number 2. Otherwise the children in both groups are treated exactly the same way. The only difference is the device used to deliver the bronchodilator. Children in both arms have the same condition and the same inclusion and exclusion criteria. In this group children are receiving salbutamol with valved holding chamber number 1. Otherwise the children in both groups are treated exactly the same way. The only difference is the device used to deliver the bronchodilator. Children in both arms have the same condition and the same inclusion and exclusion criteria.