Usefulness of Protein-enriched Infant Formula in Pediatric Intensive Care.
Protein-Energy Malnutrition
About this trial
This is an interventional prevention trial for Protein-Energy Malnutrition focused on measuring Children, Intensive Care, Nutrition, Enteral feeding, Protein intake, Protein balance., Lean Body Mass
Eligibility Criteria
Inclusion Criteria:
- Children aged 1 month to 2 years.
- Children admitted to PICU.
- Children receiving enteral nutrition with an estimated length of over 72 hours.
Exclusion Criteria: Children who met any of the following criteria will be excluded:
- Age less than 1 month or over 2 years.
- Diabetes mellitus or any inborn metabolic error.
- Parenteral nutrition.
- Bicarbonate infusion.
- Renal replacement therapy.
- Children receiving exclusive breastfeeding or in a need of special enteral formula.
Sites / Locations
- Hospital Universitario Central de AsturiasRecruiting
- Hospital Clínico Universitario de Santiago-CHUSRecruiting
- Hospital General Universitario Gregorio MarañónRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
Standard Enteral Nutrition
Protein-enriched nutrition
High Protein-enriched Nutrition
Standard Enteral Nutrition: cow's milk based infant formula (Nidina, Nestlé, Barcelona, Spain).
Protein-enriched Enteral Nutrition: polymeric infant formula (Infatrini; Nutricia, Madrid, Spain)
High Protein-enriched Enteral Nutrition: polymeric infant formula (Infatrini; Nutricia, Madrid, Spain) supplemented with 2.6 g of protein/100 mL of formula. The source of the protein supplement would be a nonhydrolyzed protein cow's milk-based formula (Resource Protein Instant; Nestlé, Barcelona, Spain). Final composition 5.1 g/100 mL.