Impact of B. Bifidum 900791 Intake on Breast Milk Characteristics of Obese Mothers
Maternal Obesity
About this trial
This is an interventional basic science trial for Maternal Obesity focused on measuring obesity, breast milk, probiotic, IL-6, CRP, Insulin, Adiponectin, Resistin, breastmilk microbiota, Bifidobacterium
Eligibility Criteria
Inclusion Criteria:
- Women in their last month of pregnancy, who were normal-weight (18.5<BMI<25kg/m2) or who were obese (BMI>30kg/m2) before pregnancy, and their children
Women recruited should have expressed their wish to have their child through normal delivery, and to breastfeed at least during the first month post-partum.
Exclusion Criteria:
- Women with chronic diseases (type 2 diabetes, renal diseases, autoimmune diseases, tumor, chronic inflammatory diseases, etc.).
- Women with a history of digestive surgery.
- Women whose children are hospitalized more than 24hours in the neonatal unit
- Women who require antibiotic treatment during the perinatal period.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Placebo Comparator
Experimental
Placebo Comparator
Experimental Obese mothers
Placebo Obese mothers
Experimental normal weight mothers
Placebo normal weight mothers
One portion (50g) of an ice-cream containing the probiotic B. bifidum 900791 (>10(exp7)/g) every other day during the last month of gestation and the first month of lactation
One portion (50g) of an ice-cream without probiotic every other day during the last month of gestation and the first month of lactation
One portion (50g) of an ice-cream containing B. bifidum 900791 (>10(exp7)/g) every other day during the last month of gestation and the first month of lactation
One portion (50g) of an ice-cream without probiotic every other day during the last month of gestation and the first month of lactation