Assessment of Portable Oxygen Concentrators in Infants Undergoing Hypoxic Challenge Testing.
Hypoxia, Altitude
About this trial
This is an interventional treatment trial for Hypoxia, Altitude focused on measuring Infants, Hypoxia Altitude Simulation Test, Oxygen Delivery Device, Portable Oxygen Concentrator, Hypoxic Challenge Testing
Eligibility Criteria
Inclusion Criteria:
Patients with baseline Sat.O2 >94% AND
- <1 year with neonatal respiratory disease
- required oxygen supply in the last 6 months
- chronic respiratory disease (eg cystic fibrosis, obstructive or restrictive pulmonary disease) with FEV 1 (forced expiratory volume in 1 second) or FVC (forced vital capacity) <50%.
Exclusion Criteria:
- acute respiratory infection
Sites / Locations
- Hospital Son Espases
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
cPOC - pPOC
pPOC - cPOC
Randomized crossover study (according to a random number table): Patients are allocated randomly to two study groups (cPOC/pPOC). In case of Sat.O2 drop ≤ 85% during HCT, oxygen is administered by cPOC (continuous-flow). For patients who show a positive POC hypoxic reversal, HCT is repeated at 24 hours and oxygen is administered by pPOC (pulsed-flow).
Randomized crossover study (according to a random number table): Patients are allocated randomly to two study groups (cPOC/pPOC). In case of Sat.O2 drop ≤ 85% during HCT, oxygen is administered by pPOC (pulsed-flow). For patients who show a positive POC hypoxic reversal, HCT is repeated at 24 hours and oxygen is administered by cPOC (continuous-flow).