Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children
Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time, Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit
About this trial
This is an interventional other trial for Effect of Anesthesia in Postoperative Pain
Eligibility Criteria
Inclusion Criteria:
- children,
- American Society Anesthesia I, II,
- ambulatory surgery
Exclusion Criteria:
- Allergy to anesthetic and analgesic drugs,
- history of neuromuscular,
- renal, neurological, hepatic disease,
- craniofacial anomalies,
- Obstructive Sleep Apnea,
- obesity,
- cardiopulmonary diseases
Sites / Locations
- Childrens Hospital P. and A. Kyriakou Anesthesiology Department
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
opiod free general anesthesia
opioid based general anesthesia
In group A opioid free anesthesia is administered. Anesthesia and analgesia were achieved with ketamine(1mg/kg, bolus), dexmedetomidine(1mcg/kg, over 10 minutes), local anesthetic(ropivacaine 2mg/kg 0.75% wound infiltration), paracetamol(15mg/kg), non steroid analgesics(diclofenac 1mg/kg). Anesthesia induction with ketamine(1mg/kg), propofol 1% 2-3mg/kg, rocuronium 1mg/kg. Anesthesia maintenance with propofol 1% 10mg/kg/hour. Reversal of rocuronium with sugammadex 2mg/kg.
In group B opioid based anesthesia is administered.Anesthesia and analgesia were achieved with remifentanil(0.3mcg/kg/minute), local anesthetic(ropivacaine 2mg/kg 0.75% wound infiltration), paracetamol(15mg/kg), non steroid analgesics(diclofenac 1mg/kg).Anesthesia induction with propofol 1% 2-3mg/kg,fentanyl(2mcg/kg), rocuronium 1mg/kg. Anesthesia maintenance with propofol 1% 10mg/kg/hour. Reversal of rocuronium with sugammadex 2mg/kg.