Deep-Learning Image Reconstruction in CCTA
Coronary Artery Disease
About this trial
This is an interventional diagnostic trial for Coronary Artery Disease
Eligibility Criteria
Inclusion Criteria:
- Patients referred for cardiac CT angiography
- Age ≥ 18 years
- Written informed consent
Exclusion Criteria:
- Pregnancy or breast-feeding
- Enrollment of the investigator, his/her family members, employees and other dependent persons
- Renal insufficiency (GFR below 35 mL/min/1.73 m²)
Sites / Locations
- University Hospital
Arms of the Study
Arm 1
Other
Normal-dose versus Low-dose
The standard intervention consists of the routinely performed cardiac CT datasets reconstructed with a standard iterative reconstruction algorithm (ASIR-V). Median radiation dose is about 0.5 mSv, range between about 0.2 and 1.2 mSv; median contrast agent administration about 45 mL, range between 35 and 55 mL. The experimental intervention is an additional CT scan with a lower dose (about 20 to 50% decrease) and a similar contrast agent administration that is reconstructed with a deep-learning image reconstruction immediately after the clinical CT scan. The additional time required is about 5 minutes.