Effect of an Anti-inflammatory Diet on Patients With Cervical Cancer
Cervical Cancer, Uterine Cervical Neoplasm, Pelvic Inflammatory Disease
About this trial
This is an interventional supportive care trial for Cervical Cancer focused on measuring Cancer, Intestinal inflammation, Diet
Eligibility Criteria
Inclusion Criteria:
- Ability to understand the study and provide informed consent.
- ECOG: 0-2.
- Willingness to assist to every programed visit, to keep to the dietary intervention and lab tests.
- Diagnosed with cervical cancer.
- Clinical stages IB-2-IVA.
- Candidate to receive concomitant chemo-radiotherapy followed by brachytherapy.
- Disease measured by CT scan.
- No previous treatment based on chemo-radiotherapy. Hemoglobina levels >10g/dL.
- Leucocytes >4000/mm3.
- Platelets > 100000/mm3.
- Adequate hepatic function.
Exclusion Criteria:
- Patients under nutritional treatment or supplement.
- Patients with active uncontrolled infections.
- Patients under treatment with an experimental drug.
- Patients with fistula at the moment of diagnosis.
- Patients with previous malignancy.
Sites / Locations
- Instituto Nacional de Cancerologia
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Anti-inflammatory Diet
Low residue Diet
Dietary intervention providing: Energy: 28-31 kcal/kg/day. Protein: 20-30%. Fat: 30-40%. Carbohydrates: 40-50%. The diet will be individualized according to the patients' comorbidities (obesity, type 2 diabetes, hypertension, renal insufficiency). This group will include the consumption of foods that contain immune modulating nutrients: Omega-3 fatty acids, antioxidants, soluble fiber, probiotics. The recommendation to include these foods will be made according to the patients' access to food in their home area.
Dietary intervention providing: Energy: 28-31 kcal/kg/day. Protein: 20%. Fat: 20%. Carbohydrates: 60%. Diet will have lactose restriction, fiber restriction and fat restriction.