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A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC) (CheckMate 8HW)

Primary Purpose

Metastatic Colorectal Cancer

Status
Recruiting
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Ipilimumab
Oxaliplatin
Leucovorin
Fluorouracil
Irinotecan
Bevacizumab
Cetuximab
Nivolumab
Sponsored by
Bristol-Myers Squibb
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Metastatic Colorectal Cancer

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Histologically confirmed recurrent or metastatic colorectal cancer (CRC) irrespective of prior treatment history with chemotherapy and/or targeted agents not amenable to surgery (Applicable only during Part 1 enrollment of the study)
  • Histologically confirmed recurrent or metastatic CRC with no prior treatment history with chemotherapy and/or targeted agents for metastatic disease and not amenable to surgery (Applicable during Part 2 enrollment of the study)
  • Known tumor microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) status per local standard of practice
  • Eastern cooperative oncology group (ECOG) performance status lower than or equal to 1

Exclusion Criteria:

  • An active, known or suspected autoimmune disease
  • History of interstitial lung disease or pneumonitis
  • Known history of positive test for human immunodeficiency virus (HIV) or known acquired immunodeficiency syndrome (AIDS)

Other protocol-defined inclusion/exclusion criteria apply

Sites / Locations

  • Local Institution
  • Local Institution - 0059
  • Local Institution - 0130
  • Local Institution - 0103
  • Local Institution
  • Local Institution
  • Local Institution - 0119
  • Local Institution - 0060
  • Local Institution - 0105
  • Local Institution
  • Local Institution - 0121
  • Local Institution - 0106
  • Local Institution
  • Local Institution - 0104
  • Local Institution - 0073
  • Local Institution - 0074
  • Local Institution - 0084
  • Local Institution - 0100
  • Local Institution - 0072
  • Local Institution - 0019Recruiting
  • Local Institution - 0053Recruiting
  • Local Institution - 0018Recruiting
  • Local Institution - 0041Recruiting
  • Local Institution - 0017Recruiting
  • Local Institution - 0064
  • Local Institution - 0068
  • Local Institution - 0120
  • Local Institution - 0067
  • Local Institution - 0065
  • Local Institution - 0045
  • Local Institution
  • Local Institution - 0025
  • Local Institution - 0024
  • Local Institution - 0096
  • Local Institution - 0200
  • Local Institution - 0192
  • Local Institution - 0102
  • Local Institution - 0094
  • Local Institution - 0199
  • Local Institution - 0095
  • Local Institution - 0193
  • Local Institution - 0011
  • Local Institution - 0039
  • Local Institution
  • Local Institution - 0013
  • Local Institution - 0016
  • Local Institution - 0015
  • Local Institution
  • Local Institution - 0071Recruiting
  • Local Institution - 0069
  • Local Institution - 0070Recruiting
  • Local Institution - 0146
  • Local Institution
  • Local Institution - 0163Recruiting
  • Local Institution - 0207Recruiting
  • Local Institution - 0211Recruiting
  • Local Institution - 0158Recruiting
  • Local Institution - 0194
  • Local Institution - 0167Recruiting
  • Local Institution - 0153Recruiting
  • Local Institution - 0149Recruiting
  • Local Institution - 0160Recruiting
  • Local Institution - 0196Recruiting
  • Local Institution - 0180Recruiting
  • Local Institution - 0181Recruiting
  • Local Institution - 0197Recruiting
  • Local Institution - 0145Recruiting
  • Local Institution - 0151Recruiting
  • Local Institution - 0164Recruiting
  • Local Institution - 0162Recruiting
  • Local Institution - 0188Recruiting
  • Local Institution - 0210Recruiting
  • Local Institution - 0212Recruiting
  • Local Institution - 0154Recruiting
  • Local Institution - 0165
  • Local Institution - 0143
  • Local Institution - 0131Recruiting
  • Local Institution - 0195Recruiting
  • Local Institution - 0137Recruiting
  • Local Institution - 0206Recruiting
  • Local Institution - 0087
  • Local Institution - 0085
  • Local Institution - 0088
  • Local Institution - 0086
  • Local Institution - 0038
  • Local Institution
  • Local Institution - 0036
  • Local Institution - 0176Recruiting
  • Local Institution - 0138Recruiting
  • Local Institution - 0186Recruiting
  • Local Institution - 0028Recruiting
  • Local Institution - 0029Recruiting
  • Local Institution - 0183
  • Local Institution - 0066Recruiting
  • Local Institution - 0030Recruiting
  • Local Institution - 0032Recruiting
  • Local Institution - 0027Recruiting
  • Local Institution - 0061Recruiting
  • Local Institution - 0031Recruiting
  • Local Institution
  • Local Institution - 0184
  • Local Institution - 0040Recruiting
  • Local Institution - 0042
  • Local Institution - 0007
  • Local Institution - 0043
  • Local Institution - 0117
  • Local Institution - 0008
  • Local Institution - 0009
  • Local Institution - 0044
  • Local Institution - 0010
  • Local Institution - 0123Recruiting
  • Local Institution - 0125
  • Local Institution - 0124Recruiting
  • Local Institution - 0126Recruiting
  • Local Institution - 0091
  • Local Institution - 0022
  • Local Institution - 0026
  • PO Garibaldi Nesima AORN GaribaldiRecruiting
  • Local Institution - 0003
  • ASST Grande Ospedale NiguardaRecruiting
  • AOU della Campania Luigi VanvitelliRecruiting
  • I.O.V. Istituto Oncologico Veneto IrcssRecruiting
  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro CuoreRecruiting
  • Local Institution - 0109Recruiting
  • Local Institution - 0112Recruiting
  • Local Institution - 0107Recruiting
  • Local Institution - 0132Recruiting
  • Local Institution - 0116Recruiting
  • Local Institution - 0174Recruiting
  • Local Institution - 0128Recruiting
  • Local Institution - 0111Recruiting
  • Local Institution - 0175Recruiting
  • Local Institution - 0133Recruiting
  • Local Institution - 0189Recruiting
  • Local Institution - 0177Recruiting
  • Local Institution - 0115Recruiting
  • Local Institution - 0187Recruiting
  • Local Institution - 0110Recruiting
  • Local Institution - 0108Recruiting
  • Local Institution - 0118Recruiting
  • Local Institution - 0113Recruiting
  • Local Institution - 0129Recruiting
  • Local Institution - 0114Recruiting
  • Local Institution - 0052
  • Local Institution - 0051
  • Local Institution - 0050
  • Local Institution - 0033
  • Local Institution - 0034
  • Local Institution - 0035
  • Local Institution - 0058
  • Local Institution - 0076
  • Local Institution - 0168
  • Local Institution - 0080
  • Local Institution
  • Local Institution - 0081
  • Local Institution - 0205
  • Local Institution - 0089
  • Local Institution - 0056
  • Local Institution - 0173
  • Local Institution - 0006
  • Local Institution
  • Local Institution - 0005
  • Local Institution - 0172
  • Local Institution - 0063
  • Local Institution - 0171
  • Local Institution - 0092
  • Local Institution - 0101
  • Local Institution
  • Local Institution
  • Local Institution - 0127
  • Local Institution - 0049

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm Type

Experimental

Experimental

Active Comparator

Arm Label

Arm A: Nivolumab Monotherapy

Arm B: Nivolumab + Ipilimumab Combination

Arm C: Investigator's Choice Chemotherapy

Arm Description

Participants in Arm C would be allowed to receive Nivolumab + Ipilimumab if they progress

Outcomes

Primary Outcome Measures

Progression-Free Survival (PFS) by Blinded Independent Central Review (BICR) (arm B vs A, all lines, centrally confirmed)
PFS by BICR (arm B vs C, 1L, centrally confirmed)

Secondary Outcome Measures

Overall Response Rate (ORR) by BICR (arm B vs A, all lines, centrally confirmed)
Overall Survival (OS) (arm B vs A, all lines, centrally confirmed)
PFS by Investigator Assessment (arm B vs A, all lines, centrally confirmed)
PFS by BICR among all randomized participants (arm B vs A, all lines, per local testing)
PFS by BICR (arm B vs A, 1L, centrally confirmed)
ORR by BICR (arm B vs C, 1L, centrally confirmed)
ORR by BICR (arm B vs A, 1L, centrally confirmed)
OS (arm B vs A, 1L, centrally confirmed)
PFS by BICR (arm A vs C, 1L, centrally confirmed)
OS (arm B vs C, 1L, centrally confirmed)
ORR by BICR (arm A vs C, 1L, centrally confirmed)
OS (arm A vs C, 1L, centrally confirmed)
PFS by Investigator (arm A, B and C, 1L, centrally confirmed)
PFS by BICR among all randomized participants who have not received prior treatment (arm B vs C, 1L, per local testing)
PFS by BICR among all randomized participants who have not received prior treatment (arm B vs A, 1L, per local testing)
PFS by BICR (arm B vs C, 1L, by each central test)
PFS by BICR (arm B vs A, all lines, by each central test)
PFS by BICR (crossover cohort, centrally confirmed)
ORR by BICR (crossover cohort, centrally confirmed)

Full Information

First Posted
July 2, 2019
Last Updated
October 20, 2023
Sponsor
Bristol-Myers Squibb
Collaborators
Ono Pharmaceutical Co. Ltd
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1. Study Identification

Unique Protocol Identification Number
NCT04008030
Brief Title
A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)
Acronym
CheckMate 8HW
Official Title
A Phase 3 Randomized Clinical Trial of Nivolumab Alone, Nivolumab in Combination With Ipilimumab, or Investigator's Choice Chemotherapy in Participants With Microsatellite Instability High (MSI-H) or Mismatch Repair Deficient (dMMR) Metastatic Colorectal Cancer
Study Type
Interventional

2. Study Status

Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
August 5, 2019 (Actual)
Primary Completion Date
June 9, 2025 (Anticipated)
Study Completion Date
June 10, 2026 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Bristol-Myers Squibb
Collaborators
Ono Pharmaceutical Co. Ltd

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The main purpose of this study is to compare the clinical benefit, as measured by Progression-Free Survival (PFS), Objective Response Rate (ORR), and Overall Survival (OS), achieved by nivolumab in combination with ipilimumab or by nivolumab monotherapy in participants with Microsatellite Instability High (MSI-H) or Mismatch Repair Deficient (dMMR) metastatic colorectal cancer (mCRC). This study will also compare nivolumab plus ipilimumab combination vs chemotherapy for treatment of MSI-H/dMMR mCRC participants.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Metastatic Colorectal Cancer

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
831 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Arm A: Nivolumab Monotherapy
Arm Type
Experimental
Arm Title
Arm B: Nivolumab + Ipilimumab Combination
Arm Type
Experimental
Arm Title
Arm C: Investigator's Choice Chemotherapy
Arm Type
Active Comparator
Arm Description
Participants in Arm C would be allowed to receive Nivolumab + Ipilimumab if they progress
Intervention Type
Biological
Intervention Name(s)
Ipilimumab
Intervention Description
Specified dose on specified days
Intervention Type
Drug
Intervention Name(s)
Oxaliplatin
Intervention Description
Specified dose on specified days
Intervention Type
Drug
Intervention Name(s)
Leucovorin
Intervention Description
Specified dose on specified days
Intervention Type
Drug
Intervention Name(s)
Fluorouracil
Intervention Description
Specified dose on specified days
Intervention Type
Drug
Intervention Name(s)
Irinotecan
Intervention Description
Specified dose on specified days
Intervention Type
Drug
Intervention Name(s)
Bevacizumab
Intervention Description
Specified dose on specified days
Intervention Type
Drug
Intervention Name(s)
Cetuximab
Intervention Description
Specified dose on specified days
Intervention Type
Biological
Intervention Name(s)
Nivolumab
Intervention Description
Specified dose on specified days
Primary Outcome Measure Information:
Title
Progression-Free Survival (PFS) by Blinded Independent Central Review (BICR) (arm B vs A, all lines, centrally confirmed)
Time Frame
Up to 5 years
Title
PFS by BICR (arm B vs C, 1L, centrally confirmed)
Time Frame
Up to 5 years
Secondary Outcome Measure Information:
Title
Overall Response Rate (ORR) by BICR (arm B vs A, all lines, centrally confirmed)
Time Frame
Up to 5 years
Title
Overall Survival (OS) (arm B vs A, all lines, centrally confirmed)
Time Frame
Up to 5 years
Title
PFS by Investigator Assessment (arm B vs A, all lines, centrally confirmed)
Time Frame
Up to 5 years
Title
PFS by BICR among all randomized participants (arm B vs A, all lines, per local testing)
Time Frame
Up to 5 years
Title
PFS by BICR (arm B vs A, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
ORR by BICR (arm B vs C, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
ORR by BICR (arm B vs A, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
OS (arm B vs A, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
PFS by BICR (arm A vs C, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
OS (arm B vs C, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
ORR by BICR (arm A vs C, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
OS (arm A vs C, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
PFS by Investigator (arm A, B and C, 1L, centrally confirmed)
Time Frame
Up to 5 years
Title
PFS by BICR among all randomized participants who have not received prior treatment (arm B vs C, 1L, per local testing)
Time Frame
Up to 5 years
Title
PFS by BICR among all randomized participants who have not received prior treatment (arm B vs A, 1L, per local testing)
Time Frame
Up to 5 years
Title
PFS by BICR (arm B vs C, 1L, by each central test)
Time Frame
Up to 5 years
Title
PFS by BICR (arm B vs A, all lines, by each central test)
Time Frame
Up to 5 years
Title
PFS by BICR (crossover cohort, centrally confirmed)
Time Frame
Up to 5 years
Title
ORR by BICR (crossover cohort, centrally confirmed)
Time Frame
Up to 5 years

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Histologically confirmed recurrent or metastatic colorectal cancer (CRC) irrespective of prior treatment history with chemotherapy and/or targeted agents not amenable to surgery (Applicable only during Part 1 enrollment of the study) Histologically confirmed recurrent or metastatic CRC with no prior treatment history with chemotherapy and/or targeted agents for metastatic disease and not amenable to surgery (Applicable during Part 2 enrollment of the study) Known tumor microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) status per local standard of practice Eastern cooperative oncology group (ECOG) performance status lower than or equal to 1 Exclusion Criteria: An active, known or suspected autoimmune disease History of interstitial lung disease or pneumonitis Known history of positive test for human immunodeficiency virus (HIV) or known acquired immunodeficiency syndrome (AIDS) Other protocol-defined inclusion/exclusion criteria apply
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
BMS Study Connect Contact Center www.BMSStudyConnect.com
Phone
855-907-3286
Email
Clinical.Trials@bms.com
First Name & Middle Initial & Last Name or Official Title & Degree
First line of the email MUST contain NCT # and Site #.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Bristol-Myers Squibb
Organizational Affiliation
Bristol-Myers Squibb
Official's Role
Study Director
Facility Information:
Facility Name
Local Institution
City
Gilbert
State/Province
Arizona
ZIP/Postal Code
85234
Country
United States
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0059
City
Los Angeles
State/Province
California
ZIP/Postal Code
90033
Country
United States
Individual Site Status
Completed
Facility Name
Local Institution - 0130
City
Sacramento
State/Province
California
ZIP/Postal Code
95817
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0103
City
Denver
State/Province
Colorado
ZIP/Postal Code
80218
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Local Institution
City
Miami
State/Province
Florida
ZIP/Postal Code
33136
Country
United States
Individual Site Status
Withdrawn
Facility Name
Local Institution
City
Marietta
State/Province
Georgia
ZIP/Postal Code
30060
Country
United States
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0119
City
Arlington Heights
State/Province
Illinois
ZIP/Postal Code
60005
Country
United States
Individual Site Status
Completed
Facility Name
Local Institution - 0060
City
New York
State/Province
New York
ZIP/Postal Code
10065
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0105
City
Portland
State/Province
Oregon
ZIP/Postal Code
97227
Country
United States
Individual Site Status
Completed
Facility Name
Local Institution
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0121
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15232
Country
United States
Individual Site Status
Completed
Facility Name
Local Institution - 0106
City
Dallas
State/Province
Texas
ZIP/Postal Code
75246
Country
United States
Individual Site Status
Completed
Facility Name
Local Institution
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0104
City
Roanoke
State/Province
Virginia
ZIP/Postal Code
24014
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0073
City
Ciudad Autonoma Beunos Aires
State/Province
Buenos Aires
ZIP/Postal Code
1431
Country
Argentina
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0074
City
Viedma
State/Province
RIO Negro
ZIP/Postal Code
8500
Country
Argentina
Individual Site Status
Completed
Facility Name
Local Institution - 0084
City
Buenos Aires
ZIP/Postal Code
1093
Country
Argentina
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0100
City
Caba
ZIP/Postal Code
1199
Country
Argentina
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0072
City
Caba
ZIP/Postal Code
1426
Country
Argentina
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0019
City
Westmead
State/Province
New South Wales
ZIP/Postal Code
2145
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0019
Facility Name
Local Institution - 0053
City
Woolloongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0053
Facility Name
Local Institution - 0018
City
Elizabeth Vale
State/Province
South Australia
ZIP/Postal Code
5112
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0018
Facility Name
Local Institution - 0041
City
Clayton
State/Province
Victoria
ZIP/Postal Code
3168
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0041
Facility Name
Local Institution - 0017
City
Heidelberg
State/Province
Victoria
ZIP/Postal Code
3084
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0017
Facility Name
Local Institution - 0064
City
Graz
ZIP/Postal Code
8036
Country
Austria
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0068
City
Linz
ZIP/Postal Code
4010
Country
Austria
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0120
City
Salzburg
ZIP/Postal Code
5020
Country
Austria
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0067
City
Wiener Neustadt
ZIP/Postal Code
2700
Country
Austria
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0065
City
Wien
ZIP/Postal Code
1090
Country
Austria
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0045
City
Bonheiden
State/Province
Antwerpen
ZIP/Postal Code
2820
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
Local Institution
City
Brussel
ZIP/Postal Code
1090
Country
Belgium
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0025
City
Bruxelles
ZIP/Postal Code
1000
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0024
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0096
City
Ipatinga
State/Province
Minas Gerais
ZIP/Postal Code
35160-158
Country
Brazil
Individual Site Status
Completed
Facility Name
Local Institution - 0200
City
Natal
State/Province
RIO Grande DO Norte
ZIP/Postal Code
59075-740
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0192
City
Porto Alegre
State/Province
RIO Grande DO SUL
ZIP/Postal Code
91350-200
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0102
City
Barretos
State/Province
Sao Paulo
ZIP/Postal Code
14780-070
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0094
City
São José do Rio Preto
State/Province
São Paulo
ZIP/Postal Code
15090000
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0199
City
Rio de Janeiro
ZIP/Postal Code
20231-050
Country
Brazil
Individual Site Status
Completed
Facility Name
Local Institution - 0095
City
Sao Paulo
ZIP/Postal Code
01509-900
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0193
City
São Paulo
ZIP/Postal Code
01246-000
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0011
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 1Z2
Country
Canada
Individual Site Status
Completed
Facility Name
Local Institution - 0039
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 4E6
Country
Canada
Individual Site Status
Completed
Facility Name
Local Institution
City
Halifax
State/Province
Nova Scotia
ZIP/Postal Code
B3H 2Y9
Country
Canada
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0013
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 1X5
Country
Canada
Individual Site Status
Completed
Facility Name
Local Institution - 0016
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2X 3E4
Country
Canada
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0015
City
Sherbrooke
State/Province
Quebec
ZIP/Postal Code
J1H 5N4
Country
Canada
Individual Site Status
Completed
Facility Name
Local Institution
City
Quebec
ZIP/Postal Code
G1R 2J6
Country
Canada
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0071
City
Santiago
State/Province
Metropolitana
ZIP/Postal Code
7500921
Country
Chile
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0071
Facility Name
Local Institution - 0069
City
Santiago
State/Province
Metropolitana
ZIP/Postal Code
8320000
Country
Chile
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0070
City
Independencia
State/Province
Santiago
Country
Chile
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0070
Facility Name
Local Institution - 0146
City
Hefei
State/Province
Anhui
ZIP/Postal Code
230061
Country
China
Individual Site Status
Completed
Facility Name
Local Institution
City
Fuzhou
State/Province
Fujian
ZIP/Postal Code
350001
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0136
Facility Name
Local Institution - 0163
City
Xiamen
State/Province
Fujian
ZIP/Postal Code
361003
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0163
Facility Name
Local Institution - 0207
City
Zhangzhou
State/Province
Fujian
ZIP/Postal Code
363000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0207
Facility Name
Local Institution - 0211
City
Lanzhou
State/Province
Gansu
ZIP/Postal Code
730030
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0211
Facility Name
Local Institution - 0158
City
Foshan
State/Province
Guangdong
ZIP/Postal Code
528000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0158
Facility Name
Local Institution - 0194
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510030
Country
China
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0167
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510080
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0167
Facility Name
Local Institution - 0153
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510095
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0153
Facility Name
Local Institution - 0149
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510655
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0149
Facility Name
Local Institution - 0160
City
Nanning
State/Province
Guangxi
ZIP/Postal Code
530000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0160
Facility Name
Local Institution - 0196
City
Nanning
State/Province
Guangxi
ZIP/Postal Code
530021
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0196
Facility Name
Local Institution - 0180
City
Harbin
State/Province
Heilongjiang
ZIP/Postal Code
150040
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0180
Facility Name
Local Institution - 0181
City
Zhengzhou
State/Province
Henan
ZIP/Postal Code
450052
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0181
Facility Name
Local Institution - 0197
City
Changsha
State/Province
Hunan
ZIP/Postal Code
410013
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0197
Facility Name
Local Institution - 0145
City
Changzhou
State/Province
Jiangsu
ZIP/Postal Code
213003
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0145
Facility Name
Local Institution - 0151
City
Nanchang
State/Province
Jiangxi
ZIP/Postal Code
330006
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0151
Facility Name
Local Institution - 0164
City
Changchun
State/Province
Jilin
ZIP/Postal Code
130021
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0164
Facility Name
Local Institution - 0162
City
Shenyang
State/Province
Liaoning
ZIP/Postal Code
110042
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0162
Facility Name
Local Institution - 0188
City
Xi'an
State/Province
Shaanxi
ZIP/Postal Code
710126
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0188
Facility Name
Local Institution - 0210
City
Jinan
State/Province
Shandong
ZIP/Postal Code
250117
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0210
Facility Name
Local Institution - 0212
City
Linyi
State/Province
Shandong
ZIP/Postal Code
276034
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0212
Facility Name
Local Institution - 0154
City
Qingdao
State/Province
Shandong
ZIP/Postal Code
266061
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0154
Facility Name
Local Institution - 0165
City
Yantai
State/Province
Shandong
ZIP/Postal Code
264000
Country
China
Individual Site Status
Completed
Facility Name
Local Institution - 0143
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200080
Country
China
Individual Site Status
Completed
Facility Name
Local Institution - 0131
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200120
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0131
Facility Name
Local Institution - 0195
City
Kunming
State/Province
Yunnan
ZIP/Postal Code
650106
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0195
Facility Name
Local Institution - 0137
City
Hangzhou
State/Province
Zhejiang
ZIP/Postal Code
310009
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0137
Facility Name
Local Institution - 0206
City
Ningbo
State/Province
Zhejiang
ZIP/Postal Code
315041
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0206
Facility Name
Local Institution - 0087
City
Brno
ZIP/Postal Code
656 53
Country
Czechia
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0085
City
Hradec Kralove
ZIP/Postal Code
500 05
Country
Czechia
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0088
City
Novy Jicin
ZIP/Postal Code
741 01
Country
Czechia
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0086
City
Olomouc
ZIP/Postal Code
779 00
Country
Czechia
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0038
City
Herlev
ZIP/Postal Code
2730
Country
Denmark
Individual Site Status
Active, not recruiting
Facility Name
Local Institution
City
Odense
ZIP/Postal Code
5000
Country
Denmark
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0036
City
Vejle
ZIP/Postal Code
7100
Country
Denmark
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0176
City
Limoges
State/Province
Haute-Vienne
ZIP/Postal Code
87042
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0176
Facility Name
Local Institution - 0138
City
Lille
State/Province
Nord
ZIP/Postal Code
59000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0138
Facility Name
Local Institution - 0186
City
Bayonne
ZIP/Postal Code
64109
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0186
Facility Name
Local Institution - 0028
City
Besancon Cedex
ZIP/Postal Code
25030
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0028
Facility Name
Local Institution - 0029
City
Lyon Cedex 08
ZIP/Postal Code
69373
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0029
Facility Name
Local Institution - 0183
City
Lyon
ZIP/Postal Code
69008
Country
France
Individual Site Status
Completed
Facility Name
Local Institution - 0066
City
Marseille
ZIP/Postal Code
13005
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0066
Facility Name
Local Institution - 0030
City
Montpellier
ZIP/Postal Code
34298
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0030
Facility Name
Local Institution - 0032
City
Nantes
ZIP/Postal Code
44093
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0032
Facility Name
Local Institution - 0027
City
Paris
ZIP/Postal Code
75012
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0027
Facility Name
Local Institution - 0061
City
Pessac Cedex
ZIP/Postal Code
33604
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0061
Facility Name
Local Institution - 0031
City
Poitiers
ZIP/Postal Code
86000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0031
Facility Name
Local Institution
City
Rouen
ZIP/Postal Code
76000
Country
France
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0184
City
Strasbourg
ZIP/Postal Code
67200
Country
France
Individual Site Status
Completed
Facility Name
Local Institution - 0040
City
Toulouse
ZIP/Postal Code
31059
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0040
Facility Name
Local Institution - 0042
City
Dresden
ZIP/Postal Code
01307
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0007
City
Essen
ZIP/Postal Code
45122
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0043
City
Hamburg
ZIP/Postal Code
20249
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0117
City
Hamburg
ZIP/Postal Code
22763
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0008
City
Hannover
ZIP/Postal Code
30625
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0009
City
Heidelberg
ZIP/Postal Code
69120
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0044
City
Marburg
ZIP/Postal Code
35043
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0010
City
Munich
ZIP/Postal Code
81377
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0123
City
Athens
ZIP/Postal Code
11528
Country
Greece
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0123
Facility Name
Local Institution - 0125
City
Heraklion
ZIP/Postal Code
71110
Country
Greece
Individual Site Status
Completed
Facility Name
Local Institution - 0124
City
Holargos
ZIP/Postal Code
15562
Country
Greece
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0124
Facility Name
Local Institution - 0126
City
Ioannina
ZIP/Postal Code
45500
Country
Greece
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0126
Facility Name
Local Institution - 0091
City
Dublin 8
State/Province
Dublin
Country
Ireland
Individual Site Status
Completed
Facility Name
Local Institution - 0022
City
Dublin
Country
Ireland
Individual Site Status
Completed
Facility Name
Local Institution - 0026
City
Limerick
ZIP/Postal Code
V94 F858
Country
Ireland
Individual Site Status
Completed
Facility Name
PO Garibaldi Nesima AORN Garibaldi
City
Catania
ZIP/Postal Code
95122
Country
Italy
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Roberto Bordonaro, Site 0055
Phone
390957595936
Facility Name
Local Institution - 0003
City
Genova
ZIP/Postal Code
16132
Country
Italy
Individual Site Status
Completed
Facility Name
ASST Grande Ospedale Niguarda
City
Milan
ZIP/Postal Code
20162
Country
Italy
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Salvatore Siena, Site 0001
Phone
390264442291
Facility Name
AOU della Campania Luigi Vanvitelli
City
Napoli
ZIP/Postal Code
80131
Country
Italy
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fortunato Ciardiello, Site 0004
Phone
390815666760
Facility Name
I.O.V. Istituto Oncologico Veneto Ircss
City
Padova
ZIP/Postal Code
35128
Country
Italy
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sara Lonardi, Site 0002
Phone
390498215910
Facility Name
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore
City
Roma
ZIP/Postal Code
00168
Country
Italy
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Giampaolo Tortora, Site 0054
Phone
+390630154953
Facility Name
Local Institution - 0109
City
Nagoya-shi
State/Province
Aichi
ZIP/Postal Code
4648681
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0109
Facility Name
Local Institution - 0112
City
Chiba-shi
State/Province
Chiba
ZIP/Postal Code
260-8717
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0112
Facility Name
Local Institution - 0107
City
Kashiwa-shi
State/Province
Chiba
ZIP/Postal Code
2778577
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0107
Facility Name
Local Institution - 0132
City
Matsuyama
State/Province
Ehime
ZIP/Postal Code
791-0280
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0132
Facility Name
Local Institution - 0116
City
Fukuoka-shi
State/Province
Fukuoka
ZIP/Postal Code
8111395
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0116
Facility Name
Local Institution - 0174
City
Sapporo-shi
State/Province
Hokkaido
ZIP/Postal Code
0608648
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0174
Facility Name
Local Institution - 0128
City
Kanazawa-city
State/Province
Ishikawa
ZIP/Postal Code
9208641
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0128
Facility Name
Local Institution - 0111
City
Kawasaki-shi
State/Province
Kanagawa
ZIP/Postal Code
2168511
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0111
Facility Name
Local Institution - 0175
City
Yokohama
State/Province
Kanagawa
ZIP/Postal Code
241-8515
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0175
Facility Name
Local Institution - 0133
City
Kumamoto-shi
State/Province
Kumamoto
ZIP/Postal Code
8608556
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0133
Facility Name
Local Institution - 0189
City
Osaki
State/Province
Miyagi
ZIP/Postal Code
9896183
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0189
Facility Name
Local Institution - 0177
City
Kurashiki
State/Province
Okayama
ZIP/Postal Code
7108602
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0177
Facility Name
Local Institution - 0115
City
Suita-shi
State/Province
Osaka
ZIP/Postal Code
565-0871
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0115
Facility Name
Local Institution - 0187
City
Hidaka
State/Province
Saitama
ZIP/Postal Code
350-1298
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0187
Facility Name
Local Institution - 0110
City
Kitaadachigun
State/Province
Saitama
ZIP/Postal Code
362-0806
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0110
Facility Name
Local Institution - 0108
City
Sunto-gun
State/Province
Shizuoka
ZIP/Postal Code
4118777
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0108
Facility Name
Local Institution - 0118
City
Chuo-ku
State/Province
Tokyo
ZIP/Postal Code
1040045
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0118
Facility Name
Local Institution - 0113
City
Koto-ku
State/Province
Tokyo
ZIP/Postal Code
135-8550
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0113
Facility Name
Local Institution - 0129
City
Minato-ku
State/Province
Tokyo
ZIP/Postal Code
1058470
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0129
Facility Name
Local Institution - 0114
City
Osaka
ZIP/Postal Code
540-0006
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0114
Facility Name
Local Institution - 0052
City
Amsterdam
ZIP/Postal Code
1066 CX
Country
Netherlands
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0051
City
Amsterdam
ZIP/Postal Code
1105 AZ
Country
Netherlands
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0050
City
Utrecht
ZIP/Postal Code
3584 CX
Country
Netherlands
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0033
City
Bergen
ZIP/Postal Code
5021
Country
Norway
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0034
City
Lorenskog
ZIP/Postal Code
1478
Country
Norway
Individual Site Status
Completed
Facility Name
Local Institution - 0035
City
Oslo
ZIP/Postal Code
0450
Country
Norway
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0058
City
Rio Piedras
ZIP/Postal Code
00935
Country
Puerto Rico
Individual Site Status
Completed
Facility Name
Local Institution - 0076
City
Cluj-Napoca
State/Province
Cluj
ZIP/Postal Code
400015
Country
Romania
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0168
City
Brasov
ZIP/Postal Code
002200
Country
Romania
Individual Site Status
Completed
Facility Name
Local Institution - 0080
City
Bucharest
ZIP/Postal Code
022328
Country
Romania
Individual Site Status
Active, not recruiting
Facility Name
Local Institution
City
Constanta
ZIP/Postal Code
900591
Country
Romania
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0081
City
Craiova
ZIP/Postal Code
200542
Country
Romania
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0205
City
Iași
ZIP/Postal Code
700483
Country
Romania
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0089
City
Suceava
ZIP/Postal Code
720237
Country
Romania
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0056
City
Badalona
State/Province
Barcelona [Barcelona]
ZIP/Postal Code
08916
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0173
City
A Coruna
ZIP/Postal Code
15006
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0006
City
Barcelona
ZIP/Postal Code
08035
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Local Institution
City
Madrid
ZIP/Postal Code
28034
Country
Spain
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0005
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0172
City
Malaga
ZIP/Postal Code
29010
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0063
City
Sevilla
ZIP/Postal Code
41013
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0171
City
Valencia
ZIP/Postal Code
46014
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0092
City
Adana
ZIP/Postal Code
01060
Country
Turkey
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0101
City
Istanbul
ZIP/Postal Code
34300
Country
Turkey
Individual Site Status
Active, not recruiting
Facility Name
Local Institution
City
London
State/Province
Greater London
ZIP/Postal Code
SE1 9RY
Country
United Kingdom
Individual Site Status
Withdrawn
Facility Name
Local Institution
City
Leeds
State/Province
Yorkshire
ZIP/Postal Code
LS9 7TF
Country
United Kingdom
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0127
City
London
ZIP/Postal Code
EC1A 7BE
Country
United Kingdom
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0049
City
Oxford
ZIP/Postal Code
OX3 7LE
Country
United Kingdom
Individual Site Status
Active, not recruiting

12. IPD Sharing Statement

Links:
URL
https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html
Description
BMS Clinical Trial Information
URL
https://www.bmsstudyconnect.com/s/US/English/USenHome
Description
BMS Clinical Trial Patient Recruiting
URL
https://www.fda.gov/Safety/MedWatch/SafetyInformation/default.htm
Description
FDA Safety Alerts and Recalls

Learn more about this trial

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)

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