Safety and Efficacy of Fecal Microbiota Transplantation
Crohn Disease, Ulcerative Colitis, Celiac Disease
About this trial
This is an interventional treatment trial for Crohn Disease
Eligibility Criteria
Inclusion Criteria:
Confirmed diagnosis of any of the following diseases:
- Crohn's disease
- Ulcerative colitis
- Celiac disease
- Irritable bowel syndrome
- Functional dyspepsia
- Constipation
- Antibiotic-associated diarrhea or any antibiotic- associated complications/symptoms
- Metabolic syndrome such as diabetes mellitus and obesity
- Multidrug-resistant infection
- Hepatic encephalopathy
- Multiple sclerosis
- Pseudo-obstruction
- Carbapenem-resistant Enterobacteriaceae (CRE) or Vancomycin-resistant Enterococci (VRE) infection
- Multiple organ dysfunction
- Dysbiotic bowel syndrome
- MRSA enteritis
- Pseudomembranous enteritis
- Alopecia, autism
- Graft-versus-host disease
- Idiopathic thrombocytopenic purpura (ITP)
- Atopy or allergy
- Liver disease such as Nonalcoholic fatty liver disease (NAFLD) and Nonalcoholic steatohepatitis (NASH)
- Alcohol dependence
- Psoriatic arthropathy that has suboptimal control of disease despite standard treatment.
Exclusion Criteria:
- Known contraindication to all FMT infusion method such as nasoduodenal tube insertion, oesophago-gastro-duodenoscopy (OGD), enteroscopy, colonoscopy and enema
- Any conditions that may render the efficacy of FMT or at the discretion of the investigators
- Current pregnancy
Sites / Locations
- The Chinese University of Hong KongRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Arm 7
Arm 8
Arm 9
Arm 10
Arm 11
Arm 12
Arm 13
Arm 14
Arm 15
Arm 16
Arm 17
Arm 18
Arm 19
Arm 20
Arm 21
Arm 22
Arm 23
Arm 24
Arm 25
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Crohn's disease
Ulcerative colitis
Celiac disease
Irritable bowel syndrome
Functional dyspepsia
Constipation
Metabolic disease (diabetes mellitus or obesity)
Multidrug-resistant infection
Hepatic encephalopathy
Multiple sclerosis
Pseudo-obstruction
CRE infection
VRE infection
Multiple organ dysfunction
Dysbiotic bowel syndrome
MRSA enteritis
Pseudomembranous enteritis
Alopecia
Autism
Graft-versus-host disease
Idiopathic thrombocytopenic purpura
Atopy or allergy
Liver disease
Alcohol dependence
Antibiotic-associated diarrhea
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.
Fecal Microbiota Transplant will be performed.