Repetitive Transcranial Magnetic Stimulation for Post-Stroke Visual Field Defects
Visual Fields Hemianopsia, Stroke, Ischemic, Stroke Hemorrhagic
About this trial
This is an interventional treatment trial for Visual Fields Hemianopsia focused on measuring Transcranial Magnetic Stimulation
Eligibility Criteria
Inclusion Criteria:
- Patients with a brain imaging showing vascular lesion involving visual cortical area
- Duration of at least 3 months.
Exclusion Criteria:
- Visual field defects of ophthalmologic origin
- Causes of severe visual impairment other than visual field defects
- Drug abuse
- Past history or family history of epilepsy
- Skull bone defects
- Implanted metallic devices
Sites / Locations
- Neuromodulation Research Lab, Neurology Department, Ain Shams University Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Sham Comparator
Active Group
Sham Group
A total of 16, every other day sessions of rTMS at 10 Hz frequency will be applied to 4 locations along the perilesional area (see target selection). Intensity will be 100% of motor threshold, 25 trains - 40 pulses per train with 20 seconds intertrain interval and a total of 1000 pulses per session. The coil handle will be directed downwards at 45º of the sagittal plain to ensure that the induced electric field be perpendicular to the underlying gyrus.
Sham group will receive the same sessions as above with the exact same parameters yet a sham coil identical in shape and size to the active coil will be used instead. The sham coil produces sounds and sensations very similar to the active one.