Trial on Damage Control Surgery for Perforated Diverticulitis With Generalized Peritonitis (Damage Control)
Damage Control for Perforated Diverticulitis
About this trial
This is an interventional treatment trial for Damage Control for Perforated Diverticulitis
Eligibility Criteria
Inclusion Criteria:
- All patients with clinical and radiological suspicion of colonic perforation and generalized Peritonitis with indication for emergency surgery were included in the study and intraoperatively confirmed generalized peritonitis
Exclusion Criteria:
- Covered perforation or peritonitis limited to one quadrant
- No colonic perforation (gastric perforation, appendicitis, ...)
- Malignancy as cause of perforation
- Age < 18 years
- Pregnancy
- Preoperative anal incontinence
- No patient consent
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Damage control surgery
Control group
In the damage control surgery (DCS) group the surgeon was asked to perform rapid source control by stapling the perforated segment leaving blind ends or suturing the perforation site if possible, doing a thorough lavage of the abdominal cavity and placing an intra-abdominal negative pressure system avoiding the retraction of the abdominal wall with dynamic sutures as published. The second-look operation was scheduled for a time 24-48 hours after primary surgery that would be during regular working hours with a colorectal surgeon on hand to make the decision for either anastomosis or ostomy.
In the conventional treatment group (Group C), the decision to reconstruct the colon or perform a Hartmann procedure was made by the surgeon during the emergency operation. After performing the anastomosis or the Hartmann procedure, patients with advanced peritonitis received an intraabdominal negative pressure system at the discretion of the operating surgeon.