Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain
Necrotic Pulp
About this trial
This is an interventional treatment trial for Necrotic Pulp focused on measuring etidronate, postoperative pain, bacterial load reduction, sodium hypochlorite irrigation
Eligibility Criteria
Inclusion Criteria:
- Patients who are free from any physical or mental handicapping condition with no underlying systemic disease.
Mandibular permanent premolar teeth:
- Diagnosed clinically with pulp necrosis.
- Absence of spontaneous pain
- Slight widening in the periodontal membrane space or with a periapical radiolucency
- Patients' acceptance to participate in the trial.
- Patients who can understand pain scale and can sign the informed consent
Exclusion Criteria:
- Medically compromised patients: Pain levels and healing following treatment would be compromised as these patients have shown higher incidence of pain and lower healing rate.
- Pregnant women: Avoid radiation exposure, anesthesia, and medication.
- If analgesics or antibiotics have been administrated by the patient during the past 24 hours preoperatively might alter their pain perception.
- Patients reporting bruxism or clenching: Avoid further pressure on an already inflamed tooth inducing subsequent irritation and inflammation.
- Teeth that shows association with acute periapical abscess and swelling:
Need special treatment steps which could involve additional visits with incision and drainage. Also, it could influence initiation and progression of postoperative pain.
- Greater than grade I mobility or pocket depth greater than 5 mm. Need special surgical and/or periodontal therapy.
- Hopeless tooth.
- Vital teeth.
- Immature teeth.
- Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
etidronate in sodium hypochlorite
sodium hypochlorite
It comes in a capsule containing 0.9 g of etidronate powder, which should be mixed immediately with 10 mL of a NaOCl solution of choice directly before treatment, resulting in a combined irrigant containing both active chlorine and approximately 9% etidronate. Irrigation with a total volume of 25 ml for each case
irrigation with 2.5% NaOCl with a total volume of 25 ml for each case