Can Amino Acid Supplementation Augment the Anabolic Response in Tendon After Exercise
Tendinopathy
About this trial
This is an interventional basic science trial for Tendinopathy focused on measuring tendon, amino acid, exercise
Eligibility Criteria
Inclusion Criteria:
- 21-35 years or 60-80 years old
Exclusion Criteria:
- diabetes
- BMI>35
- acute illness, cardiac, pulmonary, liver, or kidney abnormalities, uncontrolled hypertension, metabolic disorders, arthritis, or a history of neuromuscular problems.
- chronic pain medication users
- alcoholism
- competitive athletes
- pregnant women will be excluded
- Individuals with specific allergies to amino acids
Sites / Locations
- Purdue University
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Young
Older Adults
21-30 year old men and women Inclusion/Exclusion Criteria All subjects will be sedentary or recreationally active (sedentary: one day or less per week of aerobic or resistance exercise for at least a year or recreationally active: not training for competitive events). Age: 21-30 years Body mass index <35 kg•m-2, Chronic users of medications such as acetaminophen, ibuprofen, or prescription cyclooxygenase inhibitors will be excluded as these medications have been shown to alter tendon physiology. Individuals with diabetes will be excluded. Diabetes is thought to change the structure of tendon. Individuals with a history of tendon pain will be excluded, as chronic tendon pain is associated with changes in the structure of tendon. Persons with allergies/sentivitiy to amino acids or ingedianet of Cystal Light will be excluded.
Inclusion/Exclusion Criteria All subjects will be sedentary or recreationally active (sedentary: one day or less per week of aerobic or resistance exercise for at least a year or recreationally active: not training for competitive events). Age: 60-75 years Body mass index <35 kg•m-2 Chronic users of medications such as acetaminophen, ibuprofen, or prescription cyclooxygenase inhibitors will be excluded as these medications have been shown to alter tendon physiology. Individuals with diabetes will be excluded. Diabetes is thought to change the structure of tendon. Individuals with a history of tendon pain will be excluded, as chronic tendon pain is associated with changes in the structure of tendon. Persons with allergies/sentivitiy to amino acids or ingedianet of Cystal Light will be excluded.