Xenogenic Collagen Matrix and Subepithelial Connective Tissue Graft in the Treatment of Gingival Recession
Gingival Recession Localized Moderate
About this trial
This is an interventional treatment trial for Gingival Recession Localized Moderate focused on measuring Xenogenic collagen matrix (XCM)., subepithelial connective tissue graft (SCGT)., coronally advanced flap (CAF)., Root coverage.
Eligibility Criteria
Inclusion Criteria:
- Good general health.
- No contraindications for periodontal surgery.
- Presence of one localized gingival recession in each side of the maxilla and/or mandible, All recessions will be Class I defects (Miller 1985).
- The cemento-enamel junction (CEJ) is visible in the defective teeth.
- All patients demonstrating good plaque control.
- No previous periodontal surgery in the targeted area.
Exclusion Criteria:
- Smokers.
- pregnant or nursing patients.
- history of malignancy, radiotherapy, or chemotherapy.
- Patients taking medications that affect mucosal healing.
- Patients with allergy to collagen.
- Previous participation in a clinical trial.
- Type-1 diabetes patients.
- Patient who have diseases that affect connective tissue metabolism.
Sites / Locations
- Department of Periodontics, University of Damascus Dental School
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
(XCM)+(CAF)
(SCTG)+(CAF)
Surgical protocol for test treatment with CAF + XCM: After local anesthetizing the recipient site,CAF elevation will be done using (De Sanctis & Zucchelli 2007) design.Horizontal incisions will be done at the recession site,another two slightly divergent vertical incisions will be done at the end of previous incisions extending to the mucogingival junction.The resulting flap will be split thickness in the surgical papillae area,then will be full thickness exposing 3-4 mm of the bone apically of the dehiscence and after that it will be split thickness in the apical direction,all the muscle insertions will be eliminated,the root surface will be prepared by curettes and chemically treated with 24% EDTA gel.De-epithelialization of the interdental papillae will be done.The XCM will be trimmed and fix onto the root surface 1-2mm coronally of the CEJ using absorbable sutures,and the flap will be coronally advanced to fully cover the XCM and then sutured to the de-epithelialized papillae.
The surgical protocol in the control group will be identical with test group protocol with these exceptions: The entire flap will be elevated as split thickness instead of split-full-split thickness flap. A SCTG harvested from the palate will be used to cover the exposed denuded root surface in lieu of placement of XCM in the test group. And absorbable sutures will be used to stabilize it 2 mm coronally from the CEJ. As in the test group the mucosal flap will coronally advanced to completely cover the SCTG then sutured to the de-epithelialized papillae.