Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis
Chronic Periodontitis, Periodontal Pocket, Periodontal Attachment Loss
About this trial
This is an interventional supportive care trial for Chronic Periodontitis focused on measuring Chronic Periodontitis, Autologous fibrin tissue adhesive, Blood Platelets, Non-surgical periodontal therapy
Eligibility Criteria
Inclusion Criteria:
- Being diagnosed with moderate/severe chronic periodontitis;
- Being older than 18 years;
- Presence of at least three teeth in each quadrant with ≥5 mm probing pocket; depth and ≥3 mm clinical attachment loss;
- Being systemically healthy;
- Not smoking cigarettes.
Exclusion Criteria:
- Presence of a systemic disease (diabetes, hypertension, coagulopathy, radiotherapy, chemotherapy, etc.);
- Use of any drugs that could influence the results of the study;
- Periodontal treatment in the last six months before the study, or use of antibiotics in the last six months;
- Smoking or alcohol consumption;
- Pregnancy.
Sites / Locations
- Faculty of Dentistry, Department of Periodontology, İnonu University
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Placebo Comparator
Placebo Comparator
Experimental
Experimental
Subgroups:control and initial pocket depths:5-6mm
Subgroups:control and initial pocket depths≥7mm
Subgroups:AFG and initial pocket depths:5-6mm
Subgroups:AFG and initial pocket depths≥7mm
Control group divided into two subgroups according to initial pocket depths and this subgroup includes initial pocket depths:5-6mm
Control group divided into two subgroups according to initial pocket depths and this subgroup includes initial pocket depths higher than 7mm
AFG group divided into two subgroups according to initial pocket depths and this subgroup includes initial pocket depths:5-6mm
AFG group divided into two subgroups according to initial pocket depths and this subgroup includes initial pocket depths higher than 7mm