A Patch Free Treatment for Young Children With Amblyopia
Amblyopia, Binocular Vision Disorder
About this trial
This is an interventional treatment trial for Amblyopia focused on measuring Amblyopia, Binocular treatment, Visual acuity, Stereopsis, Motor function
Eligibility Criteria
Inclusion Criteria:
- Aged 3-5.9 years old (36-83 months at the time of registration)
- Confirmed diagnosis of amblyopia
- Best-corrected visual acuity of 20/32 - 20/100 in the amblyopic eye
- Best-corrected visual acuity of 20/16 - 20/40 in fellow eye for ages 3-4, and 20/16-20/32 for ages 5-5.9
- Interocular difference in visual acuity of 3 lines or greater
- If anisometropic, anisometropia (≥1.00D)
- Wearing glasses for 8+ weeks + no change in VA w/ glasses for 4-6 weeks
- Must be able to experience simultaneous perception when viewing the binocular treatment stimuli with an appropriate interocular contrast offset
- Doctor and parent must be willing to forego patching/drops for 4 week study period
Exclusion Criteria:
- strabismus
- Diagnosed eye disease or visual disorder other than amblyopia or anisometropia
- >8 weeks premature
- Diagnosed or suspected developmental delay (eg. learning disability, autism, Down syndrome)
- Diagnosed systemic disease (eg. diabetes, lupus, albinism)
Sites / Locations
- Retina Foundation of the Southwest
- Queensland University of Technology
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Experimental
Binocular cartoon treatment at home
Control group
Binocular cartoon treatment in office
Participants will view a dichoptic binocular cartoon (provided by BBC) on the Nintendo 3DS-XL at home. They will continue to watch the cartoon for 60 minutes, 4 times a week, for 2 weeks. After 2 weeks, they will be given the option to continue for an additional 2 weeks (total of 4 weeks). Watching the cartoon does not require any special glasses. They will discontinue patching during this time.
Participants will patch for 2 hours every day at home. After 2 weeks, they will be given the option to crossover to the teratment group for an additional 2 weeks (total of 4 weeks). Patching is a common treatment for amblyopia, often considered the "golden standard." It is the most common comparison as a "control" group in amblyopia and vision therapy literature.
Participants will view a dichoptic binocular cartoon (provided by BBC) on the Nintendo 3DS-XL in office. They will continue to watch the cartoon for 60 minutes, 4 times a week, for 2 weeks. After 2 weeks, they will be given the option to continue for an additional 2 weeks (total of 4 weeks). Watching the cartoon does not require any special glasses. They will discontinue patching during this time.