First-in-man Study of Adult Patients Suffered From Alveolar Osteitis Treated Using Stomatological Tamponade Contipro
Alveolar Osteitis
About this trial
This is an interventional treatment trial for Alveolar Osteitis focused on measuring first-man-study, alveolitis sicca dolorosa, alveolar osteitis, alveolalgia, sodium hyaluronate, octenidine hydrochlorid, clinical study
Eligibility Criteria
Inclusion Criteria:
- Patient with diagnosed alveolar osteitis
- Minimal age limit 18 years
- Patient capable to fully understand and comply with the requirements of the study
Exclusion Criteria:
- Patient younger than 18 years
- Pregnant or lactant woman
- Patient diagnosed with cancer
- Patient with a history of radiotherapy in the head and neck area
- Patient undergone bisphosphonate treatment within the last two years
- Patient who had been given antibiotics less than two weeks prior the AO onset
- Patient with hypersensitivity or allergy to any substances contained in the tested drug
- Patient who smokes more than 10 cigarettes per day
Sites / Locations
- IchtysDent s.r.o
- University Hospital Brno, Clinic of Oral, Maxillary and Facial Surgery
- Prouzovi s.r.o.
- University Hospital Hradec Králové, Department of Dentistry
- Dentine s.r.o.
- FSmile s.r.o.
- Dentpra
- Mojmír Strnad
- MEDIKAP
- DV Dent s.r.o.
- Enta Dent s.r.o
Arms of the Study
Arm 1
Experimental
Patient cohort
Patients suffered from alveolar osteitis and treated using a Stomatological tamponade Contipro, composed of the Hyaluronic acid and Octenidine dihydrochloride. Firstly, the extraction wound had been irrigated with 2 ml of 3% solution of H2O2 to disinfect the site and then flushed by 2 ml of Aqua pro injectione to clear any remaining debris. After, the tested drug was applied into the extraction wound. This procedure was repeated on a daily basis for a maximum of 7 days or until the pain subsided below 20 mm and remained there for at least 2 days.