Antisecretory Factor In Severe Traumatic Brain Injury (AFISTBI)
Traumatic Brain Injury
About this trial
This is an interventional treatment trial for Traumatic Brain Injury focused on measuring traumatic brain injury, cerebral edema, antisecretory factor, inflammatory cytokines, cerebral oxygen monitoring, intracranial pressure, microdialysis
Eligibility Criteria
Inclusion Criteria:
Severe traumatic brain injury, Glasgow Outcome Scale (GCS) <9 at admission to NICU.
Clinical indication for insertion of intracranial pressure monitor, intracerebral oxygen pressure monitor and microdialysis catheter.
Consultation with relatives or consent from guardians.
Exclusion Criteria:
Known egg yolk allergy.
Unilateral or bilateral fixed and dilated pupil after initial operative intervention.
Sites / Locations
- Skane University HopsitalRecruiting
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Experimental
Placebo
Salovum
Egg yolk powder not enriched for antisecretory powder
Egg yolk powder enriched for antisecretory powder