Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery
Alveolar Osteitis, Impacted Tooth
About this trial
This is an interventional treatment trial for Alveolar Osteitis focused on measuring Third molar surgery, Alveolar osteitis, Platelet concentrates
Eligibility Criteria
Inclusion Criteria:
- Patients Age ≥ 18 years of age
- Willing and able to provide informed consent
- Ability to cooperate with the requirements of the study protocol
- Healthy patients without medical diseases or a history of bleeding problems
- Patients with the need of extraction of third molars
- The third molars had to be symmetrical, partially-erupted and in the Class I, Level B according to Pell & Gregory classification and in the vertical angulations according to Winter's classification.
Exclusion Criteria:
- Patients who have pre-existing abscess or cellulitis, acute pericoronitis, or pre-existing conditions such as an odontogenic cyst or tumour associated with their third molars
- Patients who were pregnant and breastfeeding
- Patients with drug usage such as bisphosphonate, steroids and antidepressants
- Patients who had a smoking habit
Sites / Locations
- Ege University
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
CGF application in the extraction socket
non-CGF application in the extraction socket
Partially impacted third molar was extracted with the help of straight elevator and third molar forceps. After extraction, any remains of the dental follicle were removed and the extraction sockets were irrigated with 60 mL of sterile saline. CGF fibrin gel was then randomly placed into one socket and wound closure was completed with silk suture.
Opposite side of the patient was considered as the control. After extraction of the third molar, dental follicle were removed and to prevent the flap laceration, bone contouring was also performed under sterile saline irrigation. Finally, wound closure was completed with silk suture.