To Compare EUS and MRCP in Detecting Choledocholithiasis in Patients of Intermediate Risk of Choledocholithiasis
Choledocholithiasis
About this trial
This is an interventional diagnostic trial for Choledocholithiasis focused on measuring EUS, MRCP, Intermediate Probability
Eligibility Criteria
Inclusion Criteria:
- Patients over 18yrs of age with suspected choledocholithiasis stratified into intermediate risk of choledocholithiasis as per European Society of Gastrointestinal Endoscopy Guidelines
Exclusion Criteria:
- Patients with Cholangitis
- Patients with hypotension
- Ultrasound or CT cross sectional image showing stone
- Patients with contraindications to MRCP (claustrophobia ,pacemaker, or any prosthesis contraindicating MR)
- Predictable impossibility to perform a complete exploration of pancreato biliary area by EUS (gastroenteroanastomosis or stenosis )
- Patients with suspected pancreato biliary malignancy or pancreato biliary malformations
- Patients with history significant alcohol intake
- Patients taking hepato toxic drugs
- Patients in whom serum hepatitis B or C antibodies are present
- Patients with confirmed history of choledocholithiasis or history of biliary sphincterotomy
- Patients not giving consent for participation
Sites / Locations
- Asian Institute of Gastroenterology
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Endosonography
Magnetic Resonance Cholangiopancreatography
Endosonography is endoscopic method to diagnose pancreatic and biliary disorders. Participants randomized to this arm will undergo diagnostic endosonography under propofol sedation in supervision of trained anesthesiologists. If choledocholithiasis is diagnosed on endosonography, patient will be subjected for endoscopic retrograde cholangiopancreatography for clearance of stone. If choledocholithiasis is not present then participants will be kept in follow-up and further evaluation will be done if clinically indicated as per discretion of treating physician.
Magnetic Resonance Cholangiopancreatography (MRCP) is non-invasive method for diagnosis of pancreatic and biliary disorders. Participants randomized to this arm will undergo MRCP. If choledocholithiasis is diagnosed on MRCP, participants will be subjected for endoscopic retrograde cholangiopancreatography for clearance of stone. If choledocholithiasis is not present then participants will be kept in follow-up and further evaluation will be done if clinically indicated as per discretion of treating physician.