Periodontal Regeneration Versus Tooth Extraction and Replacement Denture in Teeth With Periodontal Hopeless Prognosis
Periodontitis Complex

About this trial
This is an interventional treatment trial for Periodontitis Complex focused on measuring periodontitis, periodontal regeneration, tooth extraction, dental implant, fixed partial denture, survival analysis, Complication free survival, Recurrence analysis, Oral health related quality of life
Eligibility Criteria
Inclusion Criteria:
- Good general health
- Non-smokers or smokers with less than 20/day
- Good oral hygiene (FMPS<25%)
- Good control of periodontitis (FMBS<25%)
- Good compliance with treatment
- Presence of generalised stage III or IV periodontitis
- Radiographic bone loss to the apex or beyond the apex of the root at at least one interdental aspect
- Presence of severe clinical attachment level loss (>10 mm)
- Presence of clearly identifiable crest of bone in adjacent teeth
- Lack of function due to hyper mobility
- Vital or non-vital teeth
Exclusion Criteria:
- Medical contraindication to elective surgery
- Poor oral hygiene
- Incomplete control of periodontitis in the dentition
- Inadequate compliance
- Inability to provide informed consent
Sites / Locations
- Faculty of Dentistry, The University of Hong Kong
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Periodontal regeneration
Extraction and tooth replacement
Periodontal regeneration consisting of papilla preservation flaps, application of FDA approved CE marked periodontal regenerative devices, tooth splinting and root canal treatment as required.
Tooth extraction and replacement with a dental implant or a fixed partial denture following healing and reconstruction of the extraction area. Choice based on standard of practice.