Treatment Study of AV Node Reentry Tachycardia (AVNRT)
Supraventricular Tachycardia
About this trial
This is an interventional treatment trial for Supraventricular Tachycardia focused on measuring New Ablation Technique, Standard Ablation Technique
Eligibility Criteria
Inclusion Criteria:
- Weight >15 kg
- Age < 21 years old
- Simple CHD acceptable to enroll (Table 1):
Table 1. Diagnoses in Adult Patients with Simple Congenital Heart Disease
- Isolated congenital aortic valve disease
- Isolated congenital mitral valve disease (eg, except parachute valve, cleft leaflet)
- Small atrial septal defect
- Isolated small ventricular septal defect (no associated lesions)
- Mild pulmonary stenosis
- Small patent ductus arteriosus
- Repaired conditions
- Previously ligated or occluded ductus arteriosus
- Repaired secundum or sinus venosus atrial septal defect without residua
- Repaired ventricular septal defect without residua
Exclusion Criteria:
- Additional mechanism(s) for SVT in addition to AV nodal reentry tachycardia.
- Moderate or Complex Congenital Heart Disease, see tables 2 and 3.
Table 2. Diagnoses in Adult Patients with Congenital Heart Disease of Moderate Complexity
- Aorto-left ventricular fistulas
- Anomalous pulmonary venous drainage, partial or total
- Atrioventricular septal defects (partial or complete)
- Coarctation of the aorta
- Ebstein's anomaly
- Infundibular right ventricular outflow obstruction of significance
- Ostium primum atrial septal defect
- Patent ductus arteriosus (not closed)
- Pulmonary valve regurgitation (moderate to severe)
- Pulmonary valve stenosis (moderate to severe)
- Sinus of Valsalva fistula/aneurysm
- Sinus venosus atrial septal defect
- Subvalvular AS or SupraAS (except HOCM)
- Tetralogy of Fallot
- Ventricular septal defect with:
- Absent valve or valves
- Aortic regurgitation
- Coarctation of the aorta
- Mitral disease
- Right ventricular outflow tract obstruction
- Straddling tricuspid/mitral valve
- Subaortic stenosis
Table 3. Types of Adult Congenital Heart Disease - Severe Complexity
- Conduits, valved or nonvalved
- Cyanotic congenital heart (all forms)
- Double-outlet ventricle
- Eisenmenger syndrome
- Fontan procedure
- Mitral atresia
- Single ventricle (also called double inlet or outlet, common, or primitive)
- Pulmonary atresia (all forms)
- Pulmonary vascular obstructive disease
- Transposition of the great arteries
- Tricuspid atresia
- Truncus arteriosus/hemitruncus
- Other abnormalities of atrioventricular or ventriculoarterial connection not included above (ie, crisscross heart, isomerism, heterotaxy syndromes, ventricular inversion)
Sites / Locations
- Children's National HospitalRecruiting
- Memorial Health SystemRecruiting
- Univeristy of IowaRecruiting
- University of LouisvilleRecruiting
- University of WisconsinRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
New Ablation Technique
Standard Ablation Technique
Will undergo ablation using voltage mapping and triangle of Koch propagation wave collision mapping. Ablation will be performed at or slightly above the site of wave front collision.
Ablation performed using the traditional anatomical / electrogram guided ablation approach.