Evaluation of Endogenous Pain Modulation Mechanisms With Transcutaneous Electrical Nerve Stimulation
Chronic Pain
About this trial
This is an interventional other trial for Chronic Pain focused on measuring Excitatory mechanisms, Inhibitory mechanisms, Thermode(hot plate), Cold water bath, Transcutaneous electrical nerve stimulation (TENS)
Eligibility Criteria
Inclusion Criteria:
- Man or woman between 18 and 60 years old (inclusive)
Exclusion Criteria:
- Chronic pain
- Neurological disorders
- Musculoskeletal disorders
- Depression
- Raynaud syndrome
- History of non-efficacy with TENS
- History of epilepsy
- Presence of a pacemaker or metal implants
- Antidepressant
- Anticonvulsant
- Analgesics
- Caffeine
Sites / Locations
- Centre de Recherche sur le Vieillissement
Arms of the Study
Arm 1
Arm 2
Other
Other
Pain tests with the standardized protocol
Pain tests with the TENS protocol
This arm will consisted of pain tests using the standardized protocol (thermode(hot plate) and cold water bath)). The investigators will used the modified CPM testing procedure consisting of stimulus test (TS) administered before and after a conditioning stimulus (CS). For the standardized protocol, the TS will consisted of a noxius heat stimulus generated by a thermode (hot plate), applied for two minutes on the non-dominant anterior forearm. The CS will consisted of a cold pressor test (CT), wherein participants immersed their dominant forearm in a cold water bath for two minutes.
This arm will consisted of pain tests using the TENS protocol. The investigators will used the modified CPM testing procedure consisting of stimulus test (TS) administered before and after a conditioning stimulus (CS). For the TENS protocol, the TS will consisted of a noxius electrical stimulus generated by TENS, applied for 5 seconds on the non-dominant knee at a frequency of 1 Hz and 5 Hz. The CS will consisted of a noxius electrical stimulus generated by TENS' applied for 120 seconds on the non dominant knee and ankle at a frequency of 2 Hz