Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial
Lung Non-Small Cell Carcinoma, Lung Non-Small Cell Squamous Carcinoma, Lung Non-Squamous Non-Small Cell Carcinoma
About this trial
This is an interventional treatment trial for Lung Non-Small Cell Carcinoma
Eligibility Criteria
Inclusion Criteria:
- Previously registered to A151216 (NCT02194738)
- Central and/or local testing of EGFR with no EGFR exon 19 deletion or EGFR L858 R mutation (applicable to non-squamous patients only)
- Central and/or local testing of ALK with no ALK rearrangement (failed testing is considered negative) (applicable to non-squamous patients only)
Central and/or local testing of PD-L1 immunohistochemistry (IHC) using one of the following assays: DAKO 22C3, DAKO 28-8, EIL3N or SP263
- Note: Local testing results of EGFR and ALK by a local Clinical Laboratory Improvement Act (CLIA) certified laboratory is acceptable. The report must indicate the result as well as the CLIA number of the laboratory that performed the assay. Local result of PD-L1 by DAKO 22C3, Dako 28-8, EIL3N or SP263 are acceptable for enrollment on A081801. Patients with local results for EGFR, ALK and PD-L1 still need to be registered to A151216 and follow all the submissions requirements but do NOT need to wait for the results to proceed to A081801 registration
Completely resected stage IIA, IIB IIIA or IIIB (T3-4N2) non-small cell lung cancer (NSCLC) (squamous or non-squamous) with negative margins (complete R0 resection). Patients will be staged according to the 8th edition of the American Joint Committee on Cancer (AJCC) Staging Manual, 2017
- Note: Patients with pathologic N2 disease, completely resected, are eligible. However, patients known to have N2 disease prior to surgery are not eligible; guidelines do not recommend up-front surgery for this population
- Complete recovery from surgery. Registration to A081801 must be 30-77 days following surgery
- No prior neoadjuvant or adjuvant therapy for current lung cancer diagnosis
- No prior allogeneic tissue/solid organ transplant
- No current pneumonitis or history of (non-infectious) pneumonitis that required steroids
- Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial
- Age >= 18 years
- Eastern Cooperative Oncology Group (ECOG) performance status (PS): 0-1
- No active auto-immune disease that has required systemic treatment within the last 2 years (e.g., disease-modifying agents, corticosteroids, or immunosuppressive drugs). Replacement therapy (e.g., thyroxine, insulin, or physiologic corticosteroid release therapy for adrenal or pituitary insufficiency) is not considered a form of systemic treatment
- Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects. Therefore, for women of childbearing potential only, a negative pregnancy test done =< 7 days prior to registration is required
- No patients with a "currently active" second malignancy that is progressing or has required active treatment within the last 3 years. Participants with non-melanoma skin cancers or carcinoma in situ (e.g., breast carcinoma or cervical cancer in situ) that have undergone potentially curative therapy are eligible
- No hypersensitivity (>= grade 3) to pembrolizumab and/or any of its excipients
- No live vaccine within 30 days prior to registration. Examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, varicella/zoster (chicken pox), yellow fever, rabies, Bacillus Calmette-Guerin (BCG), and typhoid vaccine. Seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., FluMist) are live attenuated vaccines and are not allowed
- No known history of hepatitis B (defined as hepatitis B surface antigen [HBsAg] reactive) or known hepatitis C virus (defined as HCV ribonucleic acid [RNA] [qualitative] is detected) infection
- Absolute neutrophil count (ANC) >= 1,500/mm^3
- Platelet count >= 100,000/mm^3
- Hemoglobin >= 8 gm/dl
- Calculated (Calc.) creatinine clearance >= 45 mL/min
- Total bilirubin =< 1.5 x upper limit of normal (ULN)
- Aspartate aminotransferase (AST) / alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN)
Exclusion Criteria:
- Patients must NOT have uncontrolled intercurrent illness including, but not limited to, serious ongoing or active infection, symptomatic congestive heart failure, uncontrolled cardiac arrhythmia, unstable angina pectoris, that would limit compliance with study requirements
Sites / Locations
- Anchorage Associates in Radiation Medicine
- Anchorage Radiation Therapy Center
- Alaska Breast Care and Surgery LLC
- Alaska Oncology and Hematology LLC
- Alaska Women's Cancer Care
- Anchorage Oncology Centre
- Katmai Oncology GroupRecruiting
- Providence Alaska Medical Center
- Fairbanks Memorial HospitalRecruiting
- Banner MD Anderson Cancer Center
- Kingman Regional Medical Center
- Cancer Center at Saint Joseph's
- Banner Boswell Medical Center
- Banner University Medical Center - Tucson
- University of Arizona Cancer Center-North Campus
- Mercy Hospital Fort Smith
- CHI Saint Vincent Cancer Center Hot Springs
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - JonesboroRecruiting
- Kaiser Permanente-AnaheimRecruiting
- Kaiser Permanente-Deer Valley Medical CenterRecruiting
- Mission Hope Medical Oncology - Arroyo Grande
- PCR Oncology
- Sutter Auburn Faith HospitalRecruiting
- Sutter Cancer Centers Radiation Oncology Services-Auburn
- Kaiser Permanente-Baldwin ParkRecruiting
- Kaiser Permanente-BellflowerRecruiting
- Alta Bates Summit Medical Center-Herrick CampusRecruiting
- Providence Saint Joseph Medical Center/Disney Family Cancer Center
- Mills-Peninsula Medical Center
- Sutter Cancer Centers Radiation Oncology Services-Cameron Park
- Eden Hospital Medical Center
- John Muir Medical Center-Concord CampusRecruiting
- Sutter Davis Hospital
- City of Hope Comprehensive Cancer Center
- Epic Care-DublinRecruiting
- Kaiser Permanente DublinRecruiting
- Bay Area Breast Surgeons Inc
- Epic Care Partners in Cancer CareRecruiting
- Kaiser Permanente-FontanaRecruiting
- Kaiser Permanente-FremontRecruiting
- Palo Alto Medical Foundation-FremontRecruiting
- Kaiser Permanente-FresnoRecruiting
- Kaiser Permanente - Harbor CityRecruiting
- Kaiser Permanente-IrvineRecruiting
- UC San Diego Moores Cancer CenterRecruiting
- Loma Linda University Medical CenterRecruiting
- Tibor Rubin VA Medical CenterRecruiting
- Kaiser Permanente Los Angeles Medical CenterRecruiting
- Kaiser Permanente West Los AngelesRecruiting
- Contra Costa Regional Medical CenterRecruiting
- Fremont - Rideout Cancer CenterRecruiting
- Memorial Medical CenterRecruiting
- Kaiser Permanente-ModestoRecruiting
- Palo Alto Medical Foundation-Camino DivisionRecruiting
- Palo Alto Medical Foundation-Gynecologic Oncology
- Alta Bates Summit Medical Center - Summit Campus
- Bay Area Tumor Institute
- Kaiser Permanente Oakland-Broadway
- Kaiser Permanente-OaklandRecruiting
- Kaiser Permanente-OntarioRecruiting
- Saint Joseph Hospital - OrangeRecruiting
- Palo Alto Medical Foundation Health CareRecruiting
- Kaiser Permanente - Panorama CityRecruiting
- Kaiser Permanente-Rancho Cordova Cancer Center
- Eisenhower Medical CenterRecruiting
- Mercy Regional Cancer Center
- Mercy Oncology Center
- Kaiser Permanente- Marshall Medical Offices
- Kaiser Permanente-Redwood City
- Kaiser Permanente-RichmondRecruiting
- Kaiser Permanente-RiversideRecruiting
- Rohnert Park Cancer Center
- Kaiser Permanente-RosevilleRecruiting
- Sutter Cancer Centers Radiation Oncology Services-Roseville
- Sutter Roseville Medical CenterRecruiting
- The Permanente Medical Group-Roseville Radiation Oncology
- Kaiser Permanente Downtown CommonsRecruiting
- Sutter Medical Center SacramentoRecruiting
- University of California Davis Comprehensive Cancer CenterRecruiting
- Kaiser Permanente-South SacramentoRecruiting
- South Sacramento Cancer Center
- Saint Helena HospitalRecruiting
- Kaiser Permanente-San Diego ZionRecruiting
- California Pacific Medical Center-Pacific CampusRecruiting
- Kaiser Permanente-San FranciscoRecruiting
- Veterans Affairs Medical Center - San FranciscoRecruiting
- Kaiser Permanente-Santa Teresa-San JoseRecruiting
- Kaiser Permanente San LeandroRecruiting
- Pacific Central Coast Health Center-San Luis ObispoRecruiting
- Kaiser Permanente-San MarcosRecruiting
- Mills Health Center
- Kaiser San Rafael-GallinasRecruiting
- Kaiser Permanente Medical Center - Santa ClaraRecruiting
- Dominican Santa Cruz HospitalRecruiting
- Palo Alto Medical Foundation-Santa CruzRecruiting
- Mission Hope Medical Oncology - Santa Maria
- Kaiser Permanente-Santa RosaRecruiting
- Sutter Pacific Medical Foundation
- City of Hope South Pasadena
- Kaiser Permanente Cancer Treatment Center
- Kaiser Permanente-South San FranciscoRecruiting
- Kaiser Permanente-StocktonRecruiting
- Palo Alto Medical Foundation-SunnyvaleRecruiting
- Gene Upshaw Memorial Tahoe Forest Cancer CenterRecruiting
- City of Hope Upland
- Northbay Cancer Center
- Sutter Cancer Centers Radiation Oncology Services-Vacaville
- Kaiser Permanente Medical Center-VacavilleRecruiting
- Kaiser Permanente-VallejoRecruiting
- Sutter Solano Medical Center/Cancer CenterRecruiting
- Kaiser Permanente-Walnut CreekRecruiting
- Epic Care Cyberknife CenterRecruiting
- John Muir Medical Center-Walnut CreekRecruiting
- Presbyterian Intercommunity Hospital
- Kaiser Permanente-Woodland HillsRecruiting
- Rocky Mountain Cancer Centers-AuroraRecruiting
- The Medical Center of Aurora
- UCHealth University of Colorado HospitalRecruiting
- Boulder Community HospitalRecruiting
- Boulder Community Foothills Hospital
- Rocky Mountain Cancer Centers-BoulderRecruiting
- Rocky Mountain Cancer Centers - CentennialRecruiting
- Penrose-Saint Francis HealthcareRecruiting
- Rocky Mountain Cancer Centers-Penrose
- UCHealth Memorial Hospital CentralRecruiting
- Memorial Hospital NorthRecruiting
- Cancer Center of Colorado at Sloan's Lake
- Kaiser Permanente-FranklinRecruiting
- National Jewish Health-Main CampusRecruiting
- The Women's Imaging Center
- Porter Adventist HospitalRecruiting
- Colorado Blood Cancer Institute
- Presbyterian - Saint Lukes Medical Center - Health One
- Rocky Mountain Cancer Centers-MidtownRecruiting
- SCL Health Saint Joseph Hospital
- Rocky Mountain Cancer Centers-RoseRecruiting
- Rose Medical Center
- Western Surgical Care
- Mercy Medical Center
- Southwest Oncology PC
- Mountain Blue Cancer Care Center - Swedish
- Rocky Mountain Cancer Centers - SwedishRecruiting
- Swedish Medical Center
- The Melanoma and Skin Cancer Institute
- Poudre Valley Hospital
- Cancer Care and Hematology-Fort Collins
- National Jewish Health-Western Hematology OncologyRecruiting
- Saint Mary's Hospital and Regional Medical Center
- North Colorado Medical Center
- UCHealth Greeley Hospital
- Good Samaritan Medical Center
- Kaiser Permanente-Rock CreekRecruiting
- Rocky Mountain Cancer Centers-Lakewood
- Saint Anthony Hospital
- Rocky Mountain Cancer Centers-LittletonRecruiting
- Littleton Adventist HospitalRecruiting
- Kaiser Permanente-Lone TreeRecruiting
- Rocky Mountain Cancer Centers-Sky RidgeRecruiting
- Sky Ridge Medical Center
- Longmont United Hospital
- Rocky Mountain Cancer Centers-Longmont
- Medical Center of the Rockies
- McKee Medical Center
- Parker Adventist HospitalRecruiting
- Saint Mary Corwin Medical Center
- National Jewish Health-Northern Hematology OncologyRecruiting
- Rocky Mountain Cancer Centers-Thornton
- Smilow Cancer Hospital-Derby Care CenterRecruiting
- Smilow Cancer Hospital Care Center-FairfieldRecruiting
- Smilow Cancer Hospital Care Center at GreenwichRecruiting
- Smilow Cancer Hospital Care Center - GuilfordRecruiting
- Smilow Cancer Hospital Care Center at Saint FrancisRecruiting
- Smilow Cancer Center/Yale-New Haven Hospital
- Yale UniversityRecruiting
- Yale-New Haven Hospital North Haven Medical CenterRecruiting
- Smilow Cancer Hospital-Orange Care CenterRecruiting
- Stamford Hospital/Bennett Cancer CenterRecruiting
- Smilow Cancer Hospital-Torrington Care CenterRecruiting
- Smilow Cancer Hospital Care Center-TrumbullRecruiting
- Smilow Cancer Hospital-Waterbury Care CenterRecruiting
- Smilow Cancer Hospital Care Center - WaterfordRecruiting
- Veterans Affairs Connecticut Healthcare System-West Haven CampusRecruiting
- Beebe South Coastal Health CampusRecruiting
- Beebe Medical Center
- Delaware Clinical and Laboratory Physicians PA
- Helen F Graham Cancer CenterRecruiting
- Medical Oncology Hematology Consultants PARecruiting
- Christiana Care Health System-Christiana Hospital
- Beebe Health CampusRecruiting
- TidalHealth Nanticoke / Allen Cancer Center
- Christiana Care Health System-Wilmington Hospital
- Kaiser Permanente-Capitol Hill Medical CenterRecruiting
- MedStar Georgetown University HospitalRecruiting
- MedStar Washington Hospital CenterRecruiting
- Mount Sinai Comprehensive Cancer Center at Aventura
- Holy Cross Hospital
- Regional Cancer Center-Lee Memorial Health System
- Memorial Regional Hospital/Joe DiMaggio Children's HospitalRecruiting
- Baptist MD Anderson Cancer CenterRecruiting
- Mount Sinai Medical Center
- Orlando Health Cancer Institute
- Memorial Hospital West
- Moffitt Cancer Center-International Plaza
- Moffitt Cancer Center - McKinley Campus
- Moffitt Cancer CenterRecruiting
- Northside HospitalRecruiting
- Northeast Georgia Medical Center Braselton
- Northside Hospital - DuluthRecruiting
- Northeast Georgia Medical Center-GainesvilleRecruiting
- Northside Hospital - GwinnettRecruiting
- Lewis Cancer and Research Pavilion at Saint Joseph's/CandlerRecruiting
- Suburban Hematology Oncology Associates - Snellville
- Hawaii Cancer Care - Westridge
- Pali Momi Medical Center
- Queen's Cancer Center - Pearlridge
- The Cancer Center of Hawaii-Pali Momi
- The Queen's Medical Center - West Oahu
- Hawaii Cancer Care Inc - Waterfront Plaza
- Island Urology
- Queen's Cancer Cenrer - POB I
- Queen's Medical Center
- Straub Clinic and Hospital
- University of Hawaii Cancer Center
- Hawaii Cancer Care Inc-Liliha
- Hawaii Diagnostic Radiology Services LLC
- Kuakini Medical Center
- Queen's Cancer Center - Kuakini
- The Cancer Center of Hawaii-Liliha
- Kaiser Permanente Moanalua Medical CenterRecruiting
- Kapiolani Medical Center for Women and Children
- Straub Medical Center - Kahului Clinic
- Castle Medical Center
- Wilcox Memorial Hospital and Kauai Medical Clinic
- Saint Alphonsus Cancer Care Center-BoiseRecruiting
- Saint Luke's Cancer Institute - BoiseRecruiting
- Saint Alphonsus Cancer Care Center-CaldwellRecruiting
- Kootenai Health - Coeur d'AleneRecruiting
- Walter Knox Memorial Hospital
- Saint Luke's Cancer Institute - FruitlandRecruiting
- Idaho Urologic Institute-Meridian
- Saint Luke's Cancer Institute - MeridianRecruiting
- Saint Luke's Cancer Institute - NampaRecruiting
- Saint Alphonsus Cancer Care Center-NampaRecruiting
- Kootenai Clinic Cancer Services - Post FallsRecruiting
- Kootenai Cancer ClinicRecruiting
- Saint Luke's Cancer Institute - Twin FallsRecruiting
- Saint Anthony's Health
- Rush - Copley Medical CenterRecruiting
- Illinois CancerCare-BloomingtonRecruiting
- Illinois CancerCare-CantonRecruiting
- Memorial Hospital of Carbondale
- SIH Cancer InstituteRecruiting
- Illinois CancerCare-CarthageRecruiting
- Centralia Oncology ClinicRecruiting
- Northwestern UniversityRecruiting
- John H Stroger Jr Hospital of Cook CountyRecruiting
- University of IllinoisRecruiting
- University of Chicago Comprehensive Cancer CenterRecruiting
- Advocate Illinois Masonic Medical CenterRecruiting
- AMG Crystal Lake - OncologyRecruiting
- Carle at The RiverfrontRecruiting
- Cancer Care Specialists of Illinois - DecaturRecruiting
- Decatur Memorial HospitalRecruiting
- Illinois CancerCare-DixonRecruiting
- Advocate Good Samaritan HospitalRecruiting
- Carle Physician Group-EffinghamRecruiting
- Crossroads Cancer CenterRecruiting
- Illinois CancerCare-EurekaRecruiting
- NorthShore University HealthSystem-Evanston Hospital
- Illinois CancerCare-GalesburgRecruiting
- Western Illinois Cancer Treatment Center
- NorthShore University HealthSystem-Glenbrook Hospital
- NorthShore University HealthSystem-Highland Park Hospital
- Edward Hines Jr VA HospitalRecruiting
- Duly Health and Care JolietRecruiting
- Illinois CancerCare-Kewanee ClinicRecruiting
- Condell Memorial HospitalRecruiting
- Illinois CancerCare-MacombRecruiting
- Carle Physician Group-Mattoon/CharlestonRecruiting
- Loyola University Medical CenterRecruiting
- Trinity Medical Center
- Good Samaritan Regional Health CenterRecruiting
- UC Comprehensive Cancer Center at Silver CrossRecruiting
- Cancer Care Center of O'FallonRecruiting
- Advocate Christ Medical CenterRecruiting
- University of Chicago Medicine-Orland ParkRecruiting
- Illinois CancerCare-Ottawa ClinicRecruiting
- Advocate Lutheran General HospitalRecruiting
- Illinois CancerCare-PekinRecruiting
- OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
- Illinois CancerCare-PeoriaRecruiting
- OSF Saint Francis Radiation Oncology at Peoria Cancer Center
- Methodist Medical Center of Illinois
- OSF Saint Francis Medical Center
- Illinois CancerCare-PeruRecruiting
- Valley Radiation Oncology
- Illinois CancerCare-PrincetonRecruiting
- OSF Saint Anthony Medical CenterRecruiting
- SwedishAmerican Regional Cancer Center/ACTRecruiting
- Genesis Cancer Center - SilvisRecruiting
- Southern Illinois University School of MedicineRecruiting
- Springfield ClinicRecruiting
- Memorial Medical Center
- Southwest Illinois Health Services LLP
- Carle Cancer CenterRecruiting
- The Carle Foundation Hospital
- Illinois CancerCare - WashingtonRecruiting
- Rush-Copley Healthcare Center
- Northwest Cancer Center - Main CampusRecruiting
- Northwest Oncology LLCRecruiting
- Parkview Regional Medical CenterRecruiting
- Northwest Cancer Center - HobartRecruiting
- Saint Mary Medical CenterRecruiting
- Franciscan Health IndianapolisRecruiting
- Saint Catherine HospitalRecruiting
- Franciscan Saint Elizabeth Health - Lafayette East
- Woodland Cancer Care Center
- Franciscan Health MooresvilleRecruiting
- Franciscan Health MunsterRecruiting
- The Community HospitalRecruiting
- Women's Diagnostic Center - MunsterRecruiting
- Baptist Health Floyd
- Reid HealthRecruiting
- Memorial Hospital of South BendRecruiting
- Union Hospital
- Northwest Cancer Center - ValparaisoRecruiting
- Mary Greeley Medical CenterRecruiting
- McFarland Clinic - AmesRecruiting
- McFarland Clinic - BooneRecruiting
- Saint Anthony Regional HospitalRecruiting
- Physicians' Clinic of Iowa PCRecruiting
- Mercy HospitalRecruiting
- Oncology Associates at Mercy Medical CenterRecruiting
- Medical Oncology and Hematology Associates-West Des Moines
- Mercy Cancer Center-West Lakes
- Alegent Health Mercy Hospital
- Heartland Oncology and Hematology LLPRecruiting
- Greater Regional Medical Center
- Genesis Medical Center - East CampusRecruiting
- Genesis Cancer Care InstituteRecruiting
- Iowa Cancer SpecialistsRecruiting
- Iowa Methodist Medical Center
- Medical Oncology and Hematology Associates-Des MoinesRecruiting
- Broadlawns Medical CenterRecruiting
- Mercy Medical Center - Des MoinesRecruiting
- Mission Cancer and Blood - Laurel
- Iowa Lutheran Hospital
- McFarland Clinic - Trinity Cancer CenterRecruiting
- Trinity Regional Medical Center
- McFarland Clinic - JeffersonRecruiting
- McFarland Clinic - MarshalltownRecruiting
- Siouxland Regional Cancer CenterRecruiting
- Methodist West Hospital
- Mercy Medical Center-West Lakes
- Cancer Center of Kansas - Chanute
- Cancer Center of Kansas - Dodge City
- Cancer Center of Kansas - El Dorado
- Central Care Cancer Center - Garden City
- Central Care Cancer Center - Great Bend
- HaysMed University of Kansas Health SystemRecruiting
- Cancer Center of Kansas-Independence
- University of Kansas Cancer CenterRecruiting
- Cancer Center of Kansas-Kingman
- Lawrence Memorial HospitalRecruiting
- Cancer Center of Kansas-Liberal
- Cancer Center of Kansas-Manhattan
- Cancer Center of Kansas - McPherson
- Cancer Center of Kansas - Newton
- Olathe Health Cancer CenterRecruiting
- University of Kansas Cancer Center-Overland ParkRecruiting
- Saint Luke's South Hospital
- Cancer Center of Kansas - Parsons
- Ascension Via Christi - PittsburgRecruiting
- Cancer Center of Kansas - Pratt
- Cancer Center of Kansas - Salina
- Salina Regional Health CenterRecruiting
- Cotton O'Neil Cancer Center / Stormont Vail HealthRecruiting
- University of Kansas Health System Saint Francis CampusRecruiting
- Cancer Center of Kansas - Wellington
- University of Kansas Hospital-Westwood Cancer CenterRecruiting
- Cancer Center of Kansas-Wichita Medical Arts TowerRecruiting
- Ascension Via Christi Hospitals WichitaRecruiting
- Cancer Center of Kansas - WichitaRecruiting
- Cancer Center of Kansas - Winfield
- Flaget Memorial Hospital
- Baptist Health Corbin
- Commonwealth Cancer Center-Corbin
- Saint Elizabeth Healthcare Edgewood
- Baptist Health Hardin
- Saint Elizabeth Fort Thomas
- Baptist Health LexingtonRecruiting
- Saint Joseph Radiation Oncology Resource Center
- Saint Joseph Hospital East
- University of Kentucky/Markey Cancer CenterRecruiting
- Saint Joseph London
- Jewish Hospital
- Baptist Health LouisvilleRecruiting
- Saints Mary and Elizabeth Hospital
- UofL Health Medical Center Northeast
- Baptist Health Madisonville/Merle Mahr Cancer Center
- Baptist Health Paducah
- Jewish Hospital Medical Center South
- Christus Saint Frances Cabrini HospitalRecruiting
- LSU Health Baton Rouge-North ClinicRecruiting
- Louisiana Hematology Oncology Associates LLCRecruiting
- Mary Bird Perkins Cancer CenterRecruiting
- Our Lady of the Lake Physicians Group - Medical OncologyRecruiting
- Medical Center of Baton Rouge
- Ochsner High Grove
- Northshore Oncology Associates-Covington
- Ochsner Hematology Oncology North Shore - Covington (West Region)Recruiting
- Terrebonne General Medical CenterRecruiting
- Ochsner Medical Center KennerRecruiting
- Louisiana State University Health Science Center
- University Medical Center New OrleansRecruiting
- Ochsner Medical Center JeffersonRecruiting
- CHRISTUS Highland Medical CenterRecruiting
- Ochsner Hematology Oncology North Shore - Slidell (East Region)
- Saint Tammany Hospital Service District #2 / Slidell Memorial Hospital
- Harold Alfond Center for Cancer CareRecruiting
- Eastern Maine Medical CenterRecruiting
- Waldo County General HospitalRecruiting
- MaineHealth/SMHC Cancer Care and Blood Disorders-BiddefordRecruiting
- Lafayette Family Cancer Center-EMMCRecruiting
- Stephens Memorial Hospital
- Penobscot Bay Medical CenterRecruiting
- MaineHealth/SMHC Cancer Care and Blood Disorders-SanfordRecruiting
- Maine Medical Partners - South PortlandRecruiting
- Anne Arundel Medical CenterRecruiting
- University of Maryland/Greenebaum Cancer Center
- Greater Baltimore Medical CenterRecruiting
- Sinai Hospital of BaltimoreRecruiting
- Kaiser Permanente-Woodlawn Medical CenterRecruiting
- Johns Hopkins University/Sidney Kimmel Cancer CenterRecruiting
- UM Upper Chesapeake Medical CenterRecruiting
- UPMC Western MarylandRecruiting
- Kaiser Permanente-Gaithersburg Medical CenterRecruiting
- UM Baltimore Washington Medical Center/Tate Cancer Center
- Kaiser Permanente - Kensington Medical CenterRecruiting
- Kaiser Permanente - Largo Medical CenterRecruiting
- Kaiser Permanente Lutherville - Timonium Medical CenterRecruiting
- TidalHealth Richard A Henson Cancer InstituteRecruiting
- Northwest Hospital Center
- TidalHealth Peninsula RegionalRecruiting
- William E Kahlert Regional Cancer Center/Sinai HospitalRecruiting
- Beverly HospitalRecruiting
- Boston Medical CenterRecruiting
- Beth Israel Deaconess Medical CenterRecruiting
- Dana-Farber Cancer InstituteRecruiting
- Steward Saint Elizabeth's Medical CenterRecruiting
- Lahey Hospital and Medical CenterRecruiting
- Dana-Farber Cancer Institute at FoxboroughRecruiting
- Addison Gilbert HospitalRecruiting
- Dana Farber-Merrimack ValleyRecruiting
- Dana-Farber/Brigham and Women's Cancer Center at Milford RegionalRecruiting
- Lahey Medical Center-PeabodyRecruiting
- Berkshire Medical Center - Cancer Center
- Dana-Farber/Brigham and Women's Cancer Center at South ShoreRecruiting
- Mercy Medical Center
- Winchester HospitalRecruiting
- UMass Memorial Medical Center - University CampusRecruiting
- Hickman Cancer Center
- MyMichigan Medical Center Gratiot
- MyMichigan Medical Center Alpena
- Saint Joseph Mercy HospitalRecruiting
- Bronson Battle CreekRecruiting
- Saint Joseph Mercy BrightonRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - BrightonRecruiting
- Henry Ford Cancer Institute-Downriver
- Saint Joseph Mercy CantonRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - CantonRecruiting
- Caro Cancer Center
- Saint Joseph Mercy ChelseaRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalRecruiting
- Hematology Oncology Consultants-Clarkston
- Newland Medical Associates-Clarkston
- Henry Ford Macomb Hospital-Clinton Township
- Beaumont Hospital - DearbornRecruiting
- Henry Ford Medical Center-Fairlane
- Henry Ford HospitalRecruiting
- Ascension Saint John HospitalRecruiting
- Great Lakes Cancer Management Specialists-Doctors ParkRecruiting
- Beaumont Hospital - Farmington HillsRecruiting
- Genesee Cancer and Blood Disease Treatment CenterRecruiting
- Genesee Hematology Oncology PCRecruiting
- Genesys Hurley Cancer InstituteRecruiting
- Hurley Medical CenterRecruiting
- MyMichigan Medical Center Gladwin
- Helen DeVos Children's Hospital at Spectrum Health
- Spectrum Health at Butterworth CampusRecruiting
- Trinity Health Grand Rapids Hospital
- Academic Hematology Oncology SpecialistsRecruiting
- Great Lakes Cancer Management Specialists-Van Elslander Cancer CenterRecruiting
- Michigan Breast Specialists-Grosse Pointe Woods
- Allegiance HealthRecruiting
- Bronson Methodist HospitalRecruiting
- West Michigan Cancer CenterRecruiting
- Ascension Borgess Cancer CenterRecruiting
- Borgess Medical Center
- Sparrow HospitalRecruiting
- Hope Cancer Clinic
- Trinity Health Saint Mary Mercy Livonia HospitalRecruiting
- Great Lakes Cancer Management Specialists-Macomb Medical CampusRecruiting
- Michigan Breast Specialists-Macomb Township
- Saint Mary's Oncology/Hematology Associates of Marlette
- MyMichigan Medical Center Midland
- Toledo Clinic Cancer Centers-Monroe
- Trinity Health Muskegon HospitalRecruiting
- Lakeland Hospital Niles
- Cancer and Hematology Centers of Western Michigan - Norton ShoresRecruiting
- Ascension Providence Hospitals - NoviRecruiting
- Henry Ford Medical Center-ColumbusRecruiting
- 21st Century Oncology-Pontiac
- Hope Cancer Center
- Newland Medical Associates-Pontiac
- Saint Joseph Mercy Oakland
- Spectrum Health Reed City HospitalRecruiting
- Great Lakes Cancer Management Specialists-Rochester Hills
- Oakland Colon Rectal Associates
- Cancer Care Associates PC
- Comprehensive Medical Center PLLC
- Hematology Oncology Consultants PC
- Oakland Medical Group
- William Beaumont Hospital-Royal OakRecruiting
- Ascension Saint Mary's HospitalRecruiting
- Oncology Hematology Associates of Saginaw Valley PCRecruiting
- Lakeland Medical Center Saint Joseph
- Marie Yeager Cancer CenterRecruiting
- Henry Ford Macomb Health Center - Shelby Township
- Ascension Providence Hospitals - SouthfieldRecruiting
- Bhadresh Nayak MD PC-Sterling HeightsRecruiting
- Premier Hematology Oncology Care
- Ascension Saint Joseph HospitalRecruiting
- Munson Medical CenterRecruiting
- Michigan Institute of Urology-Town Center
- William Beaumont Hospital - TroyRecruiting
- Hematology Oncology Consultants PC-Troy
- Advanced Breast Care Center PLLCRecruiting
- Great Lakes Cancer Management Specialists-Macomb Professional BuildingRecruiting
- Macomb Hematology Oncology PC
- Michigan Breast Specialists-WarrenRecruiting
- Saint John Macomb-Oakland HospitalRecruiting
- Henry Ford West Bloomfield Hospital
- Saint Mary's Oncology/Hematology Associates of West BranchRecruiting
- University of Michigan Health - WestRecruiting
- Huron Gastroenterology PCRecruiting
- Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusRecruiting
- Riverwood Healthcare Center
- Sanford Joe Lueken Cancer CenterRecruiting
- Essentia Health Saint Joseph's Medical Center
- Fairview Ridges Hospital
- Minnesota Oncology - Burnsville
- Cambridge Medical Center
- Mercy HospitalRecruiting
- Essentia Health - Deer River ClinicRecruiting
- Essentia Health Saint Mary's - Detroit Lakes Clinic
- Essentia Health Cancer CenterRecruiting
- Essentia Health Saint Mary's Medical Center
- Miller-Dwan Hospital
- Fairview Southdale HospitalRecruiting
- Lake Region Healthcare Corporation-Cancer Care
- Essentia Health - Fosston
- Unity Hospital
- Essentia Health Hibbing ClinicRecruiting
- Fairview Clinics and Surgery Center Maple Grove
- Minnesota Oncology Hematology PA-Maplewood
- Saint John's Hospital - Healtheast
- Abbott-Northwestern Hospital
- Hennepin County Medical CenterRecruiting
- Minneapolis VA Medical Center
- Health Partners Inc
- Monticello Cancer Center
- New Ulm Medical Center
- Essentia Health - Park Rapids
- Fairview Northland Medical Center
- North Memorial Medical Health CenterRecruiting
- Mayo Clinic in RochesterRecruiting
- Coborn Cancer Center at Saint Cloud HospitalRecruiting
- Park Nicollet Clinic - Saint Louis Park
- Regions Hospital
- United Hospital
- Essentia Health SandstoneRecruiting
- Saint Francis Regional Medical Center
- Lakeview Hospital
- Sanford Thief River Falls Medical Center
- Essentia Health Virginia ClinicRecruiting
- Ridgeview Medical Center
- Rice Memorial Hospital
- Minnesota Oncology Hematology PA-Woodbury
- Sanford Cancer Center Worthington
- Fairview Lakes Medical Center
- Baptist Memorial Hospital and Cancer Center-Golden TriangleRecruiting
- Baptist Cancer Center-GrenadaRecruiting
- Gulfport Memorial Hospital
- Hattiesburg Clinic - Hematology/Oncology Clinic
- Forrest General Hospital / Cancer Center
- University of Mississippi Medical CenterRecruiting
- Baptist Memorial Hospital and Cancer Center-Union CountyRecruiting
- Baptist Memorial Hospital and Cancer Center-OxfordRecruiting
- Baptist Memorial Hospital and Cancer Center-DesotoRecruiting
- Saint Louis Cancer and Breast Institute-Ballwin
- Central Care Cancer Center - Bolivar
- Cox Cancer Center Branson
- Saint Francis Medical CenterRecruiting
- Southeast Cancer Center
- MU Health - University Hospital/Ellis Fischel Cancer CenterRecruiting
- Siteman Cancer Center at West County HospitalRecruiting
- Parkland Health Center - FarmingtonRecruiting
- Capital Region Southwest CampusRecruiting
- Freeman Health SystemRecruiting
- Mercy Hospital Joplin
- Truman Medical CentersRecruiting
- Saint Luke's Hospital of Kansas CityRecruiting
- University of Kansas Cancer Center - NorthRecruiting
- University of Kansas Cancer Center - Lee's SummitRecruiting
- Saint Luke's East - Lee's Summit
- University of Kansas Cancer Center at North Kansas City HospitalRecruiting
- Delbert Day Cancer Institute at PCRMC
- Mercy Clinic-Rolla-Cancer and Hematology
- Heartland Regional Medical Center
- Saint Louis Cancer and Breast Institute-South City
- Washington University School of MedicineRecruiting
- Veteran's Affairs Medical Center - Saint Louis
- Mercy Hospital South
- Siteman Cancer Center-South CountyRecruiting
- Missouri Baptist Medical CenterRecruiting
- Siteman Cancer Center at Christian HospitalRecruiting
- Mercy Hospital Saint LouisRecruiting
- Siteman Cancer Center at Saint Peters HospitalRecruiting
- Sainte Genevieve County Memorial HospitalRecruiting
- Mercy Hospital Springfield
- CoxHealth South Hospital
- Missouri Baptist Sullivan HospitalRecruiting
- Missouri Baptist Outpatient Center-Sunset HillsRecruiting
- Mercy Hospital Washington
- Community Hospital of AnacondaRecruiting
- Billings Clinic Cancer CenterRecruiting
- Saint Vincent Healthcare
- Saint Vincent Frontier Cancer Center
- Bozeman Deaconess HospitalRecruiting
- Saint James Community Hospital and Cancer Treatment Center
- Benefis Healthcare- Sletten Cancer InstituteRecruiting
- Great Falls Clinic
- Kalispell Regional Medical CenterRecruiting
- Saint Patrick Hospital - Community Hospital
- Community Medical HospitalRecruiting
- Nebraska Medicine-BellevueRecruiting
- CHI Health Saint Francis
- CHI Health Good SamaritanRecruiting
- Saint Elizabeth Regional Medical Center
- Cancer Partners of Nebraska - Pine LakeRecruiting
- Southeast Nebraska Cancer Center - 68th Street PlaceRecruiting
- Nebraska Cancer Specialists/Oncology Hematology West PC - MECCRecruiting
- Nebraska Methodist HospitalRecruiting
- Oncology Associates PCRecruiting
- Nebraska Medicine-Village PointeRecruiting
- Alegent Health Immanuel Medical Center
- Alegent Health Bergan Mercy Medical CenterRecruiting
- Alegent Health Lakeside Hospital
- Creighton University Medical Center
- University of Nebraska Medical CenterRecruiting
- Midlands Community Hospital
- Carson Tahoe Regional Medical Center
- Cancer and Blood Specialists-Henderson
- Comprehensive Cancer Centers of Nevada - Henderson
- Comprehensive Cancer Centers of Nevada-Horizon Ridge
- Las Vegas Cancer Center-Henderson
- OptumCare Cancer Care at Seven Hills
- Comprehensive Cancer Centers of Nevada-Southeast Henderson
- GenesisCare USA - Henderson
- Las Vegas Urology - Green Valley
- Las Vegas Urology - Pebble
- Urology Specialists of Nevada - Green Valley
- Las Vegas Urology - Pecos
- Desert West Surgery
- OptumCare Cancer Care at CharlestonRecruiting
- University Medical Center of Southern Nevada
- Hope Cancer Care of Nevada
- Cancer and Blood Specialists-Shadow
- Radiation Oncology Centers of Nevada Central
- Urology Specialists of Nevada - Central
- GenesisCare USA - Las Vegas
- HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
- Sunrise Hospital and Medical Center
- HealthCare Partners Medical Group Oncology/Hematology-San Martin
- Las Vegas Prostate Cancer Center
- Las Vegas Urology - Sunset
- Urology Specialists of Nevada - Southwest
- Radiation Oncology Centers of Nevada Southeast
- Ann M Wierman MD LTD
- Cancer and Blood Specialists-Tenaya
- Comprehensive Cancer Centers of Nevada - Northwest
- GenesisCare USA - Vegas Tenaya
- HealthCare Partners Medical Group Oncology/Hematology-Tenaya
- Las Vegas Urology - Cathedral Rock
- Las Vegas Urology - Smoke Ranch
- OptumCare Cancer Care at MountainView
- Urology Specialists of Nevada - Northwest
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation
- Comprehensive Cancer Centers of Nevada - Town Center
- Comprehensive Cancer Centers of Nevada-Summerlin
- Summerlin Hospital Medical Center
- Las Vegas Cancer Center-Medical Center
- Comprehensive Cancer Centers of Nevada
- GenesisCare USA - Fort Apache
- OptumCare Cancer Care at Fort ApacheRecruiting
- HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
- Comprehensive Cancer Centers of Nevada - Central Valley
- University Cancer Center
- Hope Cancer Care of Nevada-Pahrump
- Renown Regional Medical Center
- Saint Mary's Regional Medical Center
- Radiation Oncology Associates
- New Hampshire Oncology Hematology PA-ConcordRecruiting
- The Dana-Farber Cancer Institute at LondonderryRecruiting
- Elliot Hospital
- Solinsky Center for Cancer CareRecruiting
- Cooper Hospital University Medical Center
- Virtua Samson Cancer Center
- Virtua Memorial
- The Valley Hospital-Luckow PavilionRecruiting
- Neurosurgeons of New Jersey-Ridgewood
- Valley HospitalRecruiting
- Virtua Voorhees
- Valley Health System-Hematology/Oncology
- Lovelace Medical Center-Saint Joseph Square
- University of New Mexico Cancer CenterRecruiting
- Presbyterian Kaseman HospitalRecruiting
- Presbyterian Rust Medical Center/Jorgensen Cancer CenterRecruiting
- Hematology Oncology Associates of Central New York-Auburn
- Northwell Health Imbert Cancer Center
- Montefiore Medical Center-Einstein CampusRecruiting
- Montefiore Medical Center-Weiler Hospital
- Montefiore Medical Center - Moses CampusRecruiting
- James J Peters VA Medical CenterRecruiting
- Maimonides Medical CenterRecruiting
- Roswell Park Cancer InstituteRecruiting
- Mary Imogene Bassett HospitalRecruiting
- Cancer Institute at Saint Francis HospitalRecruiting
- Hematology Oncology Associates of Central New York-East SyracuseRecruiting
- Glens Falls HospitalRecruiting
- Northwell Health/Center for Advanced MedicineRecruiting
- Nyack Hospital
- Upstate Cancer Center at OswegoRecruiting
- Rochester General HospitalRecruiting
- University of RochesterRecruiting
- Phelps Memorial Hospital CenterRecruiting
- Stony Brook University Medical CenterRecruiting
- State University of New York Upstate Medical UniversityRecruiting
- Hematology Oncology Associates of Central New York-Onondaga HillRecruiting
- SUNY Upstate Medical Center-Community CampusRecruiting
- Upstate Cancer Center Hematology Oncology at VeronaRecruiting
- Good Samaritan Hospital Medical CenterRecruiting
- Dickstein Cancer Treatment CenterRecruiting
- Randolph Health Cancer CenterRecruiting
- Randolph Hospital
- Cone Health Cancer Center at Alamance RegionalRecruiting
- Wake Forest University at ClemmonsRecruiting
- Durham VA Medical CenterRecruiting
- Duke University Medical CenterRecruiting
- CaroMont Regional Medical CenterRecruiting
- Cone Health Cancer CenterRecruiting
- Cone Health Cancer Center at Drawbridge ParkwayRecruiting
- Margaret R Pardee Memorial HospitalRecruiting
- Cone Heath Cancer Center at Mebane
- FirstHealth of the Carolinas-Moore Regional HospitalRecruiting
- Duke Raleigh Hospital
- Annie Penn Memorial HospitalRecruiting
- Wake Forest Baptist Health - Hematology Oncology - Statesville
- Wake Forest University Health SciencesRecruiting
- Sanford Bismarck Medical CenterRecruiting
- Essentia Health Cancer Center-South University Clinic
- Sanford South University Medical Center
- Southpointe-Sanford Medical Center Fargo
- Sanford Medical Center Fargo
- Sanford Broadway Medical CenterRecruiting
- Sanford Roger Maris Cancer CenterRecruiting
- Essentia Health - Jamestown Clinic
- Cleveland Clinic Akron General
- Aultman Alliance Community Hospital
- Indu and Raj Soin Medical Center
- Strecker Cancer Center-BelpreRecruiting
- Saint Elizabeth Boardman Hospital
- Cleveland Clinic Mercy HospitalRecruiting
- Aultman Health FoundationRecruiting
- Dayton Physicians LLC-Miami Valley SouthRecruiting
- Miami Valley Hospital South
- Adena Regional Medical CenterRecruiting
- Good Samaritan Hospital - Cincinnati
- Oncology Hematology Care Inc-Kenwood
- Bethesda North Hospital
- TriHealth Cancer Institute-Westside
- TriHealth Cancer Institute-Anderson
- MetroHealth Medical CenterRecruiting
- Cleveland Clinic Cancer Center/Fairview HospitalRecruiting
- Cleveland Clinic FoundationRecruiting
- Mount Carmel East HospitalRecruiting
- Columbus Oncology and Hematology Associates IncRecruiting
- Riverside Methodist Hospital
- Grant Medical CenterRecruiting
- The Mark H Zangmeister CenterRecruiting
- Mount Carmel Health Center WestRecruiting
- Doctors HospitalRecruiting
- Miami Valley Hospital
- Dayton Physician LLC-Miami Valley Hospital NorthRecruiting
- Miami Valley Hospital North
- Delaware Health Center-Grady Cancer CenterRecruiting
- Grady Memorial HospitalRecruiting
- Dublin Methodist Hospital
- Armes Family Cancer CenterRecruiting
- Blanchard Valley Hospital
- Orion Cancer Care
- Atrium Medical Center-Middletown Regional Hospital
- Dayton Physicians LLC-AtriumRecruiting
- Central Ohio Breast and Endocrine Surgery
- Dayton Physicians LLC-Wayne
- Wayne Hospital
- Mount Carmel Grove City Hospital
- Cleveland Clinic Cancer Center IndependenceRecruiting
- Greater Dayton Cancer CenterRecruiting
- First Dayton Cancer Care
- Kettering Medical CenterRecruiting
- Fairfield Medical CenterRecruiting
- Saint Rita's Medical Center
- OhioHealth Mansfield HospitalRecruiting
- Cleveland Clinic Cancer Center MansfieldRecruiting
- Marietta Memorial HospitalRecruiting
- OhioHealth Marion General HospitalRecruiting
- Hillcrest Hospital Cancer CenterRecruiting
- Knox Community HospitalRecruiting
- Licking Memorial HospitalRecruiting
- Newark Radiation Oncology
- Mercy Health Perrysburg Cancer CenterRecruiting
- Southern Ohio Medical CenterRecruiting
- North Coast Cancer CareRecruiting
- Springfield Regional Cancer CenterRecruiting
- Springfield Regional Medical Center
- Trinity's Tony Teramana Cancer CenterRecruiting
- ProMedica Flower HospitalRecruiting
- Saint Vincent Mercy Medical Center
- University of Toledo
- Mercy Health - Saint Anne HospitalRecruiting
- Toledo Clinic Cancer Centers-ToledoRecruiting
- Dayton Physicians LLC - Troy
- Upper Valley Medical Center
- South Pointe HospitalRecruiting
- Saint Joseph Warren Hospital
- Saint Ann's HospitalRecruiting
- Cleveland Clinic Wooster Family Health and Surgery CenterRecruiting
- Wright-Patterson Medical CenterRecruiting
- Saint Elizabeth Youngstown Hospital
- Genesis Healthcare System Cancer Care CenterRecruiting
- Cancer Centers of Southwest Oklahoma ResearchRecruiting
- University of Oklahoma Health Sciences CenterRecruiting
- Integris Southwest Medical Center
- Mercy Hospital Oklahoma CityRecruiting
- Integris Cancer Institute of OklahomaRecruiting
- Saint Alphonsus Medical Center-Baker City
- Saint Charles Health System
- Clackamas Radiation Oncology Center
- Providence Cancer Institute Clackamas Clinic
- Bay Area Hospital
- Good Samaritan HospitalRecruiting
- Three Rivers Community HospitalRecruiting
- Rogue Valley Medical CenterRecruiting
- Providence Newberg Medical CenterRecruiting
- Saint Alphonsus Medical Center-OntarioRecruiting
- Providence Portland Medical CenterRecruiting
- Providence Saint Vincent Medical CenterRecruiting
- Kaiser Permanente NorthwestRecruiting
- Saint Charles Health System-Redmond
- Lehigh Valley Hospital-Cedar CrestRecruiting
- UPMC AltoonaRecruiting
- UPMC-Heritage Valley Health System BeaverRecruiting
- Lehigh Valley Hospital - MuhlenbergRecruiting
- Bryn Mawr HospitalRecruiting
- UPMC Camp HillRecruiting
- Carlisle Regional Cancer CenterRecruiting
- Christiana Care Health System-Concord Health Center
- Chambersburg Hospital
- WellSpan Medical Oncology and HematologyRecruiting
- Geisinger Medical CenterRecruiting
- Doylestown Hospital
- Fox Chase Cancer Center - East Norriton Hospital Outpatient CenterRecruiting
- Pocono Medical CenterRecruiting
- Ephrata Cancer CenterRecruiting
- Ephrata Community Hospital
- UPMC Hillman Cancer Center ErieRecruiting
- UPMC Cancer Center at UPMC HorizonRecruiting
- Adams Cancer CenterRecruiting
- UPMC Cancer Centers - Arnold Palmer PavilionRecruiting
- Oncology Hematology AssociatesRecruiting
- UPMC Hillman Cancer Center in Greenville/UPMC Horizon
- Cherry Tree Cancer CenterRecruiting
- UPMC Pinnacle Cancer Center/Community Osteopathic CampusRecruiting
- Geisinger Medical Center-Cancer Center HazletonRecruiting
- Lehigh Valley Hospital-Hazleton
- IRMC Cancer CenterRecruiting
- UPMC-Johnstown/John P. Murtha Regional Cancer CenterRecruiting
- Sechler Family Cancer CenterRecruiting
- Geisinger Medical Oncology-LewisburgRecruiting
- Lewistown Hospital
- UPMC Cancer Center at UPMC McKeesportRecruiting
- UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer PavilionRecruiting
- Riddle Memorial HospitalRecruiting
- UPMC Hillman Cancer Center - MonroevilleRecruiting
- UPMC Hillman Cancer Center in CoraopolisRecruiting
- UPMC Hillman Cancer Center - Part of Frick HospitalRecruiting
- Arnold Palmer Cancer Center Medical Oncology NorwinRecruiting
- UPMC Cancer Center-Natrona HeightsRecruiting
- UPMC Hillman Cancer Center - New CastleRecruiting
- Paoli Memorial HospitalRecruiting
- Thomas Jefferson University HospitalRecruiting
- Fox Chase Cancer CenterRecruiting
- Temple University HospitalRecruiting
- UPMC-Saint MargaretRecruiting
- UPMC-Mercy HospitalRecruiting
- University of Pittsburgh Cancer Institute (UPCI)Recruiting
- UPMC-Shadyside Hospital
- UPMC-Passavant HospitalRecruiting
- UPMC-Saint Clair Hospital Cancer CenterRecruiting
- Pottstown HospitalRecruiting
- Geisinger Cancer Services-PottsvilleRecruiting
- Community Medical CenterRecruiting
- Geisinger Medical Oncology-Selinsgrove
- UPMC Cancer Center at UPMC NorthwestRecruiting
- Geisinger Medical Group
- UPMC Cancer Center-UniontownRecruiting
- UPMC Cancer Center-WashingtonRecruiting
- UPMC West Mifflin-Cancer Center JeffersonRecruiting
- Reading HospitalRecruiting
- Geisinger Wyoming Valley/Henry Cancer CenterRecruiting
- UPMC SusquehannaRecruiting
- Divine Providence HospitalRecruiting
- Lankenau Medical CenterRecruiting
- Cancer Care Associates of YorkRecruiting
- WellSpan Health-York Cancer CenterRecruiting
- WellSpan Health-York HospitalRecruiting
- UPMC MemorialRecruiting
- Roger Williams Medical CenterRecruiting
- Smilow Cancer Hospital Care Center - WesterlyRecruiting
- Saint Joseph's/Candler - Bluffton CampusRecruiting
- Prisma Health Cancer Institute - SpartanburgRecruiting
- Roper HospitalRecruiting
- Lowcountry Hematology Oncology PA-North Charleston
- Bon Secours Saint Francis Hospital
- Lowcountry Hematology Oncology PA-West Ashley
- Medical University of South CarolinaRecruiting
- Prisma Health Cancer Institute - EasleyRecruiting
- Gibbs Cancer Center-GaffneyRecruiting
- Saint Francis HospitalRecruiting
- Prisma Health Cancer Institute - ButternutRecruiting
- Prisma Health Cancer Institute - FarisRecruiting
- Saint Francis Cancer CenterRecruiting
- Prisma Health Cancer Institute - EastsideRecruiting
- Prisma Health Cancer Institute - GreerRecruiting
- Gibbs Cancer Center-PelhamRecruiting
- South Carolina Cancer Specialists PCRecruiting
- Lowcountry Hematology Oncology PA-Mount Pleasant
- Prisma Health Cancer Institute - SenecaRecruiting
- Spartanburg Medical CenterRecruiting
- MGC Hematology Oncology-UnionRecruiting
- Lexington Medical CenterRecruiting
- Sanford Cancer Center Oncology ClinicRecruiting
- Sanford USD Medical Center - Sioux FallsRecruiting
- University Cancer Specialists - AlcoaRecruiting
- Bristol Regional Medical Center
- Ballad Health Cancer Care - KingsportRecruiting
- Wellmont Holston Valley Hospital and Medical Center
- University of Tennessee - KnoxvilleRecruiting
- Baptist Memorial Hospital and Cancer Center-MemphisRecruiting
- Hendrick Medical CenterRecruiting
- The Don and Sybil Harrington Cancer Center
- Dell Seton Medical Center at The University of Texas
- Houston Methodist San Jacinto HospitalRecruiting
- Saint Joseph Regional Cancer Center
- Parkland Memorial HospitalRecruiting
- UT Southwestern Simmons Cancer Center - RedBirdRecruiting
- UT Southwestern/Simmons Cancer Center-DallasRecruiting
- UT Southwestern/Simmons Cancer Center-Fort WorthRecruiting
- Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
- Ben Taub General Hospital
- Houston Methodist HospitalRecruiting
- Methodist Willowbrook Hospital
- Houston Methodist West HospitalRecruiting
- Houston Methodist Saint John HospitalRecruiting
- UT Southwestern Clinical Center at Richardson/PlanoRecruiting
- Houston Methodist Sugar Land Hospital
- Houston Methodist The Woodlands HospitalRecruiting
- Wellmont Medical Associates-BristolRecruiting
- Kaiser Permanente-Burke Medical CenterRecruiting
- University of Virginia Cancer CenterRecruiting
- Augusta Health Center for Cancer and Blood DisordersRecruiting
- Centra Lynchburg Hematology-Oncology Clinic IncRecruiting
- Sovah Health Martinsville
- Kaiser Permanente Tysons Corner Medical CenterRecruiting
- Bon Secours Memorial Regional Medical Center
- Bon Secours Westchester Emergency Center
- Bon Secours Saint Francis Medical Center
- Bon Secours DePaul Medical Center
- Southwest VA Regional Cancer CenterRecruiting
- Bon Secours Maryview Medical Center
- Bon Secours Saint Mary's Hospital
- Virginia Cancer InstituteRecruiting
- Bon Secours Cancer Institute at Reynolds Crossing
- VCU Massey Cancer Center at Stony PointRecruiting
- Virginia Commonwealth University/Massey Cancer Center
- VCU Community Memorial Health CenterRecruiting
- Bon Secours Health Center at Harbour View
- Providence Regional Cancer System-Aberdeen
- MultiCare Auburn Medical CenterRecruiting
- Overlake Medical Center
- PeaceHealth Saint Joseph Medical Center
- Harrison HealthPartners Hematology and Oncology-BremertonRecruiting
- Harrison Medical Center
- Highline Medical Center-Main Campus
- Providence Regional Cancer System-Centralia
- Swedish Cancer Institute-Edmonds
- Saint Elizabeth Hospital
- Providence Regional Cancer Partnership
- Saint Francis Hospital
- MultiCare Gig Harbor Medical ParkRecruiting
- Swedish Cancer Institute-Issaquah
- Kadlec Clinic Hematology and OncologyRecruiting
- Providence Regional Cancer System-Lacey
- Saint Clare Hospital
- PeaceHealth Saint John Medical CenterRecruiting
- Jefferson HealthcareRecruiting
- Harrison HealthPartners Hematology and Oncology-Poulsbo
- MultiCare Good Samaritan HospitalRecruiting
- Valley Medical CenterRecruiting
- Pacific Gynecology Specialists
- Swedish Medical Center-Ballard Campus
- Swedish Medical Center-Cherry Hill
- Swedish Medical Center-First Hill
- PeaceHealth United General Medical Center
- Providence Regional Cancer System-Shelton
- MultiCare Deaconess Cancer and Blood Specialty Center - DowntownRecruiting
- MultiCare Deaconess Cancer and Blood Specialty Center - NorthRecruiting
- Franciscan Research Center-Northwest Medical Plaza
- MultiCare Tacoma General HospitalRecruiting
- Northwest Medical Specialties PLLC
- PeaceHealth Southwest Medical Center
- Providence Saint Mary Regional Cancer Center
- North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
- Providence Regional Cancer System-Yelm
- United Hospital Center
- West Virginia University Charleston DivisionRecruiting
- Edwards Comprehensive Cancer CenterRecruiting
- WVUH-Berkely Medical Center
- West Virginia University HealthcareRecruiting
- Camden Clark Medical Center
- Langlade Hospital and Cancer CenterRecruiting
- ThedaCare Regional Cancer CenterRecruiting
- Ascension Saint Elizabeth HospitalRecruiting
- Duluth Clinic AshlandRecruiting
- Northwest Wisconsin Cancer Center
- Ascension Southeast Wisconsin Hospital - Elmbrook CampusRecruiting
- Aurora Cancer Care-Southern Lakes VLCCRecruiting
- Ascension Calumet HospitalRecruiting
- Marshfield Clinic-Chippewa Center
- Aurora Saint Luke's South Shore
- HSHS Sacred Heart HospitalRecruiting
- Marshfield Medical Center-EC Cancer CenterRecruiting
- Saint Agnes Hospital/Agnesian Cancer Center
- Ascension Saint Francis - Reiman Cancer CenterRecruiting
- Aurora Health Care Germantown Health CenterRecruiting
- Aurora Cancer Care-GraftonRecruiting
- Bellin Memorial HospitalRecruiting
- Saint Vincent Hospital Cancer Center Green BayRecruiting
- Saint Vincent Hospital Cancer Center at Saint Mary'sRecruiting
- Aurora BayCare Medical CenterRecruiting
- Aurora Cancer Care-Kenosha SouthRecruiting
- Gundersen Lutheran Medical CenterRecruiting
- Marshfield Clinic - Ladysmith Center
- William S Middleton VA Medical Center
- University of Wisconsin Carbone Cancer CenterRecruiting
- Aurora Bay Area Medical Group-MarinetteRecruiting
- Marshfield Medical Center-MarshfieldRecruiting
- Aspirus Medford HospitalRecruiting
- Ascension Columbia Saint Mary's Hospital OzaukeeRecruiting
- Aurora Cancer Care-MilwaukeeRecruiting
- Ascension Columbia Saint Mary's Hospital - MilwaukeeRecruiting
- Aurora Saint Luke's Medical CenterRecruiting
- Medical College of WisconsinRecruiting
- Aurora Sinai Medical CenterRecruiting
- Marshfield Clinic-Minocqua CenterRecruiting
- ProHealth D N Greenwald CenterRecruiting
- ThedaCare Regional Medical Center - NeenahRecruiting
- Cancer Center of Western WisconsinRecruiting
- ProHealth Oconomowoc Memorial HospitalRecruiting
- Saint Vincent Hospital Cancer Center at Oconto FallsRecruiting
- Ascension Mercy HospitalRecruiting
- Vince Lombardi Cancer Clinic - OshkoshRecruiting
- Ascension All Saints HospitalRecruiting
- Aurora Cancer Care-RacineRecruiting
- Ascension Saint Mary's Hospital
- Marshfield Medical Center-Rice LakeRecruiting
- Vince Lombardi Cancer Clinic-SheboyganRecruiting
- Ascension Saint Michael's Hospital
- Marshfield Medical Center-River Region at Stevens PointRecruiting
- Saint Vincent Hospital Cancer Center at Sturgeon BayRecruiting
- Aurora Medical Center in SummitRecruiting
- Vince Lombardi Cancer Clinic-Two RiversRecruiting
- ProHealth Waukesha Memorial HospitalRecruiting
- UW Cancer Center at ProHealth CareRecruiting
- Aspirus Regional Cancer CenterRecruiting
- Marshfield Clinic-Wausau Center
- Ascension Medical Group Southeast Wisconsin - Mayfair RoadRecruiting
- Aurora Cancer Care-Milwaukee WestRecruiting
- Aurora West Allis Medical CenterRecruiting
- Marshfield Medical Center - WestonRecruiting
- Aspirus Cancer Care - Wisconsin RapidsRecruiting
- Marshfield Clinic - Wisconsin Rapids Center
- Cheyenne Regional Medical Center-West
- Billings Clinic-Cody
- Welch Cancer Center
- FHP Health Center-Guam
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Experimental
Experimental
Arm A (platinum doublet, observation)
Arm B (platinum doublet, sequential pembrolizumab)
Arm C (platinum doublet, combination pembrolizumab)
INITIAL THERAPY: Patients receive 1 of 4 platinum doublet regimens based on the treating physician's choice of each cycle. Treatment repeats every 21 days for 4 cycles in the absence of disease progression or unacceptable toxicity. CONTINUANCE THERAPY: Patients then undergo observation. Patients also undergo ECHO as clinically indicated during screening and on the trial. Patients may undergo MRI during screening and as clinically indicated on the trial, as well as CT and blood sample collection throughout the trial. (CLOSED AS OF UPDATE #7)
INITIAL THERAPY: Patients receive 1 of 4 platinum doublet regimens* based on the treating physician's choice of each cycle and pembrolizumab IV over 25-40 minutes on day 1 of each cycle or for cycles 1 and 3 (patients enrolled after 10/14/2020). Treatment repeats every 21 days for 4 cycles in the absence of disease progression or unacceptable toxicity. CONTINUANCE THERAPY: Patients then receive pembrolizumab IV over 25-40 minutes on day 1 of each cycle. Treatment repeats every 21 days for 13 cycles or every 6 weeks for 12 cycles (patients enrolled after 10/14/2020) in the absence of disease progression or unacceptable toxicity. Patients also undergo ECHO as clinically indicated during screening and on the trial. Patients may undergo MRI during screening and as clinically indicated on the trial, as well as CT and blood sample collection throughout the trial.
INITIAL THERAPY: Patients receive 1 of 4 platinum doublet regimens* based on the treating physician's choice of each cycle and pembrolizumab IV over 25-40 minutes on day 1 of each cycle or for cycles 1 and 3 (patients enrolled after 10/14/2020). Treatment repeats every 21 days for 4 cycles in the absence of disease progression or unacceptable toxicity. CONTINUANCE THERAPY: Patients then receive pembrolizumab IV over 25-40 minutes on day 1 of each cycle. Treatment repeats every 21 days for 13 cycles or every 6 weeks for 12 cycles (patients enrolled after 10/14/2020) in the absence of disease progression or unacceptable toxicity. Patients also undergo ECHO as clinically indicated during screening and on the trial. Patients may undergo a MRI during screening and as clinically indicated on the trial, as well as CT and blood sample collection throughout the trial.