Ischemic Conditioning of the Gastric Conduit in Esophageal Cancer.
Esophageal Anastomotic Leak, Tissue Pressure of Oxygen
About this trial
This is an interventional prevention trial for Esophageal Anastomotic Leak
Eligibility Criteria
Inclusion Criteria:
- All patients requiring a esophagectomy with cervical esophagogastrostomy for esophageal cancer
- 18 or above years old
- Karnofsky>50%
- Acceptance and signing the full informed consent
Exclusion Criteria:
- Fistula tracheobronchial
- Metastatic disease
- Anatomic vascular alteration that contraindicate the embolization (congenital celiac trunk stenosis, presence of arcuate ligament, atherosclerotic stenosis, etc,..)
- Severe cardiorespiratory failure
- Refuse to collaborate in the study
Sites / Locations
- Hospital Clínico Universitario de Valencia
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Ischemic Conditioning
Control
Preoperative artery embolization prior to esophagectomy Tissue pressure of oxygen measurement in both arms by Licox system. The probe is inserted directly through the skin as a cervical drainage and it is fixed by Witzel technique in the gastric conduit. It is removed after the three measurements (intraoperatively, 24h and 48h after surgery) of the PtiO2 as a normal drainage.
Surgery without previous ischemic conditioning of the gastric conduit Tissue pressure of oxygen measurement in both arms by Licox system. The probe is inserted directly through the skin as a cervical drainage and it is fixed by Witzel technique in the gastric conduit. It is removed after the three measurements (intraoperatively, 24h and 48h after surgery) of the PtiO2 as a normal drainage.