Ultrasound-Guided Injections for Meniscal Injuries in Active-Duty Military
Tibial Meniscus Injuries, Knee Injuries, Knee Injuries and Disorders
About this trial
This is an interventional treatment trial for Tibial Meniscus Injuries focused on measuring Regenerative Medicine, Knee Pain, Meniscus Tear
Eligibility Criteria
Inclusion Criteria:
- 18-45 years old.
- At least one of the following symptoms consistent with torn meniscus: joint line pain, clicking, popping, pain with pivot or torque.
- Physical examination findings consistent with a meniscal tear: joint line tenderness; localized pain with flexion; and other provocative tests such as McMurray's and Thessaly test.
- MRI or arthroscopic evidence of meniscal tear without significant additional joint pathology.
- Failed conservative treatment for a minimum of 4 weeks, which has included rest, ice, anti-inflammatory or other medications for pain; physical therapy; with or without/ injections, including corticosteroid and/or hyaluronic acid injections.
Additional criteria: Patients who have been told by an orthopedic surgeon that they would be a candidate for arthroscopic partial meniscectomy.
Exclusion Criteria:
- Chronically locked knee.
- Greater than Kellgren-Lawrence Grade II.
- Prior surgery performed on the effected knee.
- Assessment showing anything other than degenerative tears of the medial meniscus requiring surgical intervention.
- Recent (within 6 weeks) treatment with PRP, cortisone (oral or injection), or hyaluronic injection.
- Any disease or condition the investigator feels would hinder treatment.
- Any contra-indication to lipoaspirate, including a bleeding disorder, infection, pregnancy, or allergy to anesthetic agents.
- Chronic inflammatory diseases such as rheumatoid arthritis.
- Possible joint infection including Lyme disease of the joint.
- Malignancy within the last 5 years.
Sites / Locations
- Kessler FoundationRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Micro-Fragmented Adipose Tissue
Saline
Participants will receive a single injection of normal saline (0.9%) solution into the lesion (e.g. tear) and knee joint under ultrasound guidance using an 18 gauge x 3.5 inch needle.
Participants will receive a single injection of micro-fragmented adipose tissue into the lesion (e.g. tear) and knee joint under ultrasound guidance using an 18 gauge x 3.5 inch needle.