Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants
Poor Growth in Extremely Preterm Infants, Necrotizing Enterocolitis
About this trial
This is an interventional other trial for Poor Growth in Extremely Preterm Infants focused on measuring Premature Human Milk, Pasteurized Premature Human Milk, Human Milk Donor Fortifier, Neurodevelopmental followup
Eligibility Criteria
Inclusion Criteria:
- All extremely preterm infants with gestational age less or equal to 27 weeks who are admitted to the NICU prior to day of life seven and the first enteral feeding
Exclusion Criteria:
- Infants with severe congenital anomalies such as chromosomal trisomy, congenital heart disease, and abdominal wall defect
Sites / Locations
- Crouse HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Early Routine Fortification
Selective Fortification
Human Milk Donor Fortifier added to preterm human milk (maternal or donor) when feeds of 150 ml/kg/day are reached (120Kcal/kg/day)
Human Milk Donor Fortifier added to preterm human milk (maternal or donor) only for weight gain less than 15g/kg/day after full feeds of 180 ml/kg/day are achieved (120 Kcal/kg/day). If milk of any infant in the selective fortification group gets fortified the volume will be decreased to 150 ml/kg/day to keep the total caloric intake equal.