The Effectiveness of Acupuncture for Delirium in Critically Ill Patients
Intensive Care Unit Delirium, Delirium, Agitation
About this trial
This is an interventional treatment trial for Intensive Care Unit Delirium focused on measuring Acupuncture, Critically ill, Intensive care, Delirium, Agitation
Eligibility Criteria
Inclusion Criteria:
- Age 20-90
- Apache score <30
- Patients admitted in the ICU
- Positive delirium score as: 4 or more points according to the Intensive Care Delirium Screening Checklist (ICDSC)
- Richmond Agitation-Sedation Scale (RASS): +1, +2, +3, +4 -1, -2
Exclusion Criteria:
- Coagulopathy: Prolong Prothrombin Time (PPT) activated Partial Thromboplastin Time (aPTT) more than 4 times
- Thrombocytopenia - low platelet count
- Clinically unstable: receiving two inotropic agents or Fraction of Inspired Oxygen (FiO2) >70%
- Rass score: 0, -3, -4 (at the time of enrollment)
- Primary central nervous system disorder: stroke, traumatic brain injury, central nervous system infections, brain tumors, recent intracranial surgery
- Alcohol or substance withdrawal.
Sites / Locations
- medical and surgical intensive care department, medical and the surgical ward of China Medical University HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Acupuncture group (ACU)
Control group (CON)
Patients in acupuncture group will receive traditional Chinese acupuncture combined with Tung's style acupuncture using Press Tack Needle (PYONEX Φ0.20×0.6 mm made by Seirin Corporation). The needles appear identical to the press tack placebo with the only different is the needle itself which was removed in the placebo needles. The following acupoints will be used: HT 7 (Shen Men), PC 6 (Nei Guan), Yin Tang (EX-HN 3), San Shang (55-02) (three point from Dong's acupuncture system) and the auricular Shen Men point. The treatment will use bilateral acupuncture (if patient's condition does not allow it, unilateral acupuncture will be done). The patient will lie in a supine position during the treatment. Acupuncturist will disinfect the acupoint location with an alcohol pad (70% alcohol), then the acupuncturist will press the needles sticker to the mentioned above acupoints. Interventions will be given on day 1, 3, and 5 after patient's enrolment.
Patients randomized to the control group will receive press tack placebo (made by Seirin Corporation), which looks identical to press tack needles but, with no needle element. The point selection will be identical to acupuncture group: HT 7 (Shen Men), PC 6 (Nei Guan), Yin Tang (EX-HN 3), San Shang (55-02) (three point from Dong's acupuncture system) and the auricular Shen Men point. The treatment methods and patients position will be identical to acupuncture group. Interventions will be given on day 1, 3, and 5 after patient's enrolment.