Comparison of Two Different Approaches in the Surgical Treatment of Tubal Ectopic Pregnancy

Comparison of Conventional Laparoscopy and Natural Orifice Transluminal Endoscopic Surgery in the Surgical Treatment of Tubal Ectopic Pregnancy

In this study we aim to compare conventional laparoscopy and natural orifice transluminal endoscopic surgery in the surgical treatment of ectopic pregnancy. All the patients, with an indication of surgery for ectopic pregnancy, will be asked to participate in this clinical trial. Indication of surgery will be based on clinical findings, ultrasound scans and serum hcg levels. There will be no exclusion criteria. Duration of surgery, successful completion of the operation, intraoperative data and postoperative data will be collected. All the patients will be asked to fill out quality of recovery-40 (QoR-40) questionnaire and 36-item short form health survey (SF-36) before surgery. QoR-40 questionnaire will be repeated 24 hours after surgery and repeated every 24 hours until discharge. SF-36 will be repeated at 1-month follow-up visit. Patients will be also evaluated at postoperative 3-months, and female sexual function index will be asked to be filled-out.

natural orifice transluminal endoscopic surgery, laparoscopy, ectopic pregnancy, minimally invasive surgery, quality of life, sexual function

In this arm, patients will be treated via transvaginal natural orifice transluminal endoscopic surgery

The Quality of Recovery 40 questionnaire will be self-administered by patients at different time points

Preoperatively and Postoperative every 24 hours until discharge, expected to be up to 3 days following surgery

Short form 36 item health survery (SF-36) questionnaire will be self-administered by patients at different time points

Postoperative 2 hours, 6 hours, 12 hours, 24 hours, and every 24 hours until discharge (if the patient stays longer than 1 day at the hospital), , expected to be up to 3 days following surgery

Female sexual function index (FSFI) questionnaire will be self-administered by patients at postoperative 3-months

Patients will be routinely administered pethidine hydrochloride 3x50 mg parenteral on the day of surgery. Starting from postoperative day 1 patients will be administered paracetamol 500 mg oral upon their request. In case of inadequate pain relief and the need for additional analgesic use will ve recorded.

Inclusion Criteria: Adults over 18 years of age, Diagnosis of tubal ectopic pregnancy Patient's preference to undergo salpingectomy Exclusion Criteria: Patients with contraindication to endoscopic surgery Refusal to sign informed consent.