Ketamine Versus Magnesium Sulfate in the Time and Awakening Quality of General Anesthesia.
Awakening, Post-Anesthesia Delayed
About this trial
This is an interventional treatment trial for Awakening, Post-Anesthesia Delayed focused on measuring postoperative awakening, general anesthesia, magnesium sulfate, ketamine
Eligibility Criteria
Inclusion Criteria:
- patients scheduled to undergo laparoscopic cholecystectomy, agreement to voluntarily participate in the trial and sign the free and informed consent form.
Exclusion Criteria:
- Coronary disease, ventricular atrial block II or worse, with renal failure , previous history of brain disease, dementia or other psychiatric diseases, and patients with a body mass index> 35 kg / m² , allergy to any products used in the trial, preoperative use of opioids or corticosteroids.
Sites / Locations
- Hospital da Beneficência Portuguesa de SantosRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Experimental
Experimental
Experimental
Control group
Ketamine group
Magnesium sulfate group
Magnesium / ketamine group
The patients in this group will receive general balanced anesthesia
The patients in this group will receive 0.3 mg / kg of ketamine in saline (total volume of 100 ml) 15 min before general balanced anesthetic induction
The patients in this group will receive 40 mg / kg of magnesium sulfate in saline solution (total volume of 100 ml) 15 min before general balanced anesthetic induction
The patients in this group will receive 0.15 mg / kg of ketamine + 20 mg / kg of magnesium sulfate in saline solution (total volume of 100 ml) 15 min before general balanced anesthetic induction