Efficacy of Topical Treatment With Clobetasol in Symptomatic Oral Lichen Planus.
Oral Lichen Planus
About this trial
This is an interventional treatment trial for Oral Lichen Planus focused on measuring Oral lichen planus, Treatment, Candida
Eligibility Criteria
Inclusion Criteria:
- Symptomatic oral lichen planus
- Age above 40 years
Exclusion Criteria:
- Lichenoid contact lesions
- Graft versus host disease
- Bacteria related lichenoid reaction
- Intraoral vesiculobullous diseases
- Active antibiotic treatment
- Active treatment with steroids or other immunomodulating substance
- Allergy to Clobetasol
- Severe periodontitis
- Bad oral hygiene
- Biopsy not supporting OLP
- Allergy to nystatin
- Not in menopause
- Previous or actual oral malignancy
- Participation in other medical study
Sites / Locations
- Oral surgery, Universityhospital of ScaniaRecruiting
- Oral Surgery and oral medicine, Malmö UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Placebo Comparator
Active/active
Placebo/active
Placebo/placebo
The one bottle for use in the morning has clobetasol-oral gel, and so does the bottle fore use in the evening. The oral cavity will be rinsed with 5ml oral gel during 1 minute. Nystatin will be taken 1ml 4 times daily.
The bottle for use in the morning contains placebo and one for use in the evening contains clobetasol oral gel. The oral cavity will be rinsed with 5ml oral gel during 1 minute. Nystatin will be taken 1ml 4 times daily.
Both bottles, the one for the morning and the one for use in the evening, contains placebo. The oral cavity will be rinsed with 5ml oral gel during 1 minute. Nystatin will be taken 1ml 4 times daily.