CONFIRM: Magnetic Resonance Guided Radiation Therapy (CONFIRM)
Gastric Cancer, Invasive Breast Cancer, in Situ Breast Cancer
About this trial
This is an interventional treatment trial for Gastric Cancer focused on measuring Gastric Cancer, Invasive Breast Cancer, in Situ Breast Cancer, Lymphoma, Larynx, Bladder
Eligibility Criteria
Inclusion Criteria:
- Participants must have histologically or cytologically confirmed malignancy requiring radiation
- Age 18 years of older
- ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A)
- Ability to understand and the willingness to sign a written informed consent document.
- Any further criteria listed in the specific disease site cohort
Exclusion Criteria
History of allergic reactions attributed to gadolinium-based IV contrast
-- Note: If patient will not receive contrast, this is not applicable and kidney function will not affect eligibility
- Severe claustrophobia or anxiety
- Participants who cannot undergo an MRI
- Any other exclusion criteria listed in the specific disease site cohort
Sites / Locations
- Brigham & Women's HospitalRecruiting
- Dana Farber Cancer InstituteRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Experimental
Experimental
Experimental
Experimental
Experimental
Phase I - Gastric Cancer
Phase I - Breast Cancer
Phase I - Mantle Cell Lymphoma
Phase I - Larynx
Phase I - Bladder
The research study procedures include: Screening for eligibility Study treatment including evaluations MR-image guided radiation will be administered per disease site standards. Follow up visits Questionnaires
The research study procedures include: Screening for eligibility Study treatment including evaluations MR-image guided radiation will be administered per disease site standards. Follow up visits Questionnaires
The research study procedures include: Screening for eligibility Study treatment including evaluations MR-image guided radiation will be administered per disease site standards. Follow up visits Questionnaires
The research study procedures include: Screening for eligibility Study treatment including evaluations MR-image guided radiation will be administered per disease site standards. Follow up visits Questionnaires
The research study procedures include: Screening for eligibility Study treatment including evaluations MR-image guided radiation will be administered per disease site standards. Follow up visits Questionnaires